香精油对……和……的抗菌活性

Antimicrobial Activity of Essential Oil against and .

作者信息

Tejada-Muñoz Sonia, Cortez Denny, Rascón Jesús, Chavez Segundo G, Caetano Aline C, Díaz-Manchay Rosa J, Sandoval-Bances Julio, Huyhua-Gutierrez Sonia, Gonzales Lizandro, Chenet Stella M, Tapia-Limonchi Rafael

机构信息

Instituto de Investigación de Enfermedades Tropicales, Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas, Chachapoyas 01001, Peru.

Instituto de Salud Integral Intercultural, Facultad de Ciencias de la Salud, Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas, Chachapoyas 01001, Peru.

出版信息

Pharmaceuticals (Basel). 2024 Oct 25;17(11):1430. doi: 10.3390/ph17111430.

DOI:10.3390/ph17111430

PMID:39598342

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11597097/

Abstract

: essential oil (OEO) is safe, effective, multifunctional, and widely used. This study aimed to evaluate OEO's chemical composition and antimicrobial activity in vitro against and . : The composition of OEO was determined by gas chromatography-mass spectrometry (GC-MS). : Compounds included monoterpenes with known antimicrobial activity, such as 2-menthen-1-ol (36.33%), linalyl acetate (9.26%), terpinene-4-ol (9.01%), 4-thujanol (6.33%), menthen (5.81%), sabinene (5.18%), and carvacrol methyl ether (5.14%). : OEO had a strong antimicrobial activity with a minimum inhibitory concentration (MIC) of 1.90 mg/mL for and 0.49 mg/mL for after 18 h incubation. The minimum bactericidal concentration (MBC) was 7.9 mg/mL against and 0.99 mg/mL against . Thus, OEO could be used as a natural antimicrobial against and infections.

摘要

精油（OEO）安全、有效、多功能且用途广泛。本研究旨在评估OEO的化学成分及其对[具体菌种1]和[具体菌种2]的体外抗菌活性。通过气相色谱 - 质谱联用（GC - MS）测定OEO的成分。化合物包括具有已知抗菌活性的单萜类，如2 - 薄荷醇（36.33%）、乙酸芳樟酯（9.26%）、萜品烯 - 4 - 醇（9.01%）、4 - 侧柏醇（6.33%）、薄荷烯（5.81%）、桧烯（5.18%）和香芹酚甲醚（5.14%）。OEO具有很强的抗菌活性，在孵育18小时后，对[具体菌种1]的最低抑菌浓度（MIC）为1.90毫克/毫升，对[具体菌种2]为0.49毫克/毫升。最低杀菌浓度（MBC）对[具体菌种1]为7.9毫克/毫升，对[具体菌种2]为0.99毫克/毫升。因此，OEO可作为对抗[具体菌种1]和[具体菌种2]感染的天然抗菌剂。