School of Laboratory Medicine, Youjiang Medical University for Nationalities, Baise 533000, China.
Modern Industrial College of Biomedicine and Great Health, Youjiang Medical University for Nationalities, Baise 533000, China.
Molecules. 2024 Nov 13;29(22):5331. doi: 10.3390/molecules29225331.
Heavy metal cadmium (II) residuals have inflicted severe damage to human health and ecosystems. It has become imperative to devise straightforward and highly selective sensing methods for the detection of Cd. In this work, a ratiometric benzothiazole-based fluorescence probe () was effortlessly synthesized and characterized using standard optical techniques for the visual detection of Cd with a change in color from blue to green, exhibiting a significant Stokes shift. Moreover, the binding ratio of to Cd was established as 1:1 by the Job's plot and was further confirmed by FT-IR and HNMR titrations. The ratiometric fluorescence response via the ICT mechanism was confirmed by DFT calculations. Furthermore, the limit of detection for detecting Cd was determined to be 68 nM. Furthermore, it is noteworthy that showed good performance in real water samples, paper strips, smartphone colorimetric identification, and cell imaging.
重金属镉(II)残留对人类健康和生态系统造成了严重损害。因此，设计简单、高选择性的检测 Cd 的传感方法势在必行。在这项工作中，我们轻松地合成了一种基于苯并噻唑的比率型荧光探针 ()，并通过标准光学技术对其进行了表征，该探针可用于通过颜色从蓝色变为绿色来可视化检测 Cd，同时显示出显著的斯托克斯位移。此外，通过 Job 图确定了与 Cd 的结合比为 1:1，并通过 FT-IR 和 HNMR 滴定进一步得到证实。通过 DFT 计算证实了通过 ICT 机制的比率荧光响应。此外，检测 Cd 的检测限确定为 68 nM。此外，值得注意的是，在实际水样、纸条、智能手机比色识别和细胞成像中， 表现出良好的性能。
