EFSA J. 2024 Nov 26;22(11):e9093. doi: 10.2903/j.efsa.2024.9093. eCollection 2024 Nov.
In accordance with Article 43 of Regulation (EC) No 396/2005, the European Commission requested EFSA to perform a targeted risk assessment for dimethomorph considering the residue definition and the toxicological reference values (TRVs) derived during the renewal of the approval of dimethomorph and the most recent version of the EFSA Pesticide Residues Intake Model (PRIMo) (rev.3.1). EFSA confirmed that the current TRVs are sufficiently protective for consumers, including the identified hazard indicative of endocrine disruption. Furthermore, EFSA identified all the codex maximum residue limits (CXLs) and import tolerances that are covered by existing maximum residue levels (MRLs) and performed chronic and acute dietary risk assessment to support risk managers during the decision-making. A screening of all existing MRLs was also performed. The exposure calculations performed by EFSA showed that the existing MRLs, including the ones based on CXLs or import tolerances, do not lead to consumers intake concerns.
根据欧盟委员会条例(EC)No 396/2005第43条,欧盟委员会要求欧洲食品安全局(EFSA)针对烯酰吗啉开展靶向风险评估,评估时考虑了烯酰吗啉再评审期间得出的残留定义和毒理学参考值(TRVs)以及欧洲食品安全局农药残留摄入模型(PRIMo)的最新版本(第3.1版)。欧洲食品安全局确认,当前的毒理学参考值对消费者具有充分的保护作用,包括已识别出的表明内分泌干扰的危害。此外,欧洲食品安全局确定了现有最大残留限量(MRLs)涵盖的所有食品法典委员会最大残留限量(CXLs)和进口 tolerance,并开展了慢性和急性膳食风险评估,以在决策过程中为风险管理者提供支持。还对所有现有最大残留限量进行了筛选。欧洲食品安全局进行的暴露量计算表明,现有的最大残留限量,包括基于食品法典委员会最大残留限量或进口 tolerance 的限量,不会导致消费者摄入方面的担忧。