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伴有黏膜受累的格雷厄姆-利特尔-皮卡迪-拉叙厄尔综合征:1例罕见病例

Graham-Little-Piccardi-Lassueur Syndrome with Mucosal Involvement: A Rare Case.

作者信息

Polra Rutoo Vipulkumar, Tandel Jinal Jainendrabhai, Nair Pragya Ashok

机构信息

Department of Dermatology, Shree Krishna Hospital, Bhaikaka University, Karamsad, Gujarat, India.

Dina Skin Care, Surat, Gujarat, India.

出版信息

Int J Trichology. 2023 Nov-Dec;15(6):251-254. doi: 10.4103/ijt.ijt_88_22. Epub 2024 Oct 7.

DOI:10.4103/ijt.ijt_88_22
PMID:39600425
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11588195/
Abstract

Graham-Little-Piccardi-Lassueur syndrome (GLPLS) is a type of lichen planopilaris. It mainly affects females aged 40-60 years. It is characterized by the triad of patchy cicatricial alopecia of the scalp, noncicatricial alopecia of the axilla and groin and a follicular spinous papule on the body, scalp, or both. The diagnosis is based on clinicopathological correlation. Different modalities of treatment are available with unsatisfactory responses, so early diagnosis is necessary to prevent progression and scarring alopecia. A case of GLPLS with classical features on clinical, dermoscopic, and histopathological examination is presented in a 73-year-old female.

摘要

格雷厄姆-利特尔-皮卡迪-拉叙厄尔综合征(GLPLS)是扁平苔藓样毛发角化病的一种类型。它主要影响40至60岁的女性。其特征为头皮瘢痕性斑秃、腋窝和腹股沟非瘢痕性脱发以及身体、头皮或两者上的毛囊棘状丘疹三联征。诊断基于临床病理相关性。虽有不同的治疗方式,但反应不尽人意,因此早期诊断对于预防病情进展和瘢痕性脱发很有必要。本文报告了一例73岁女性患者,其在临床、皮肤镜和组织病理学检查中具有GLPLS的典型特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c604/11588195/e0ff6a3bc48c/IJT-15-251-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c604/11588195/aa52cedbc59f/IJT-15-251-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c604/11588195/e0ff6a3bc48c/IJT-15-251-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c604/11588195/aa52cedbc59f/IJT-15-251-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c604/11588195/e36f4ce6a1f5/IJT-15-251-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c604/11588195/6139e9b92a8c/IJT-15-251-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c604/11588195/c98af54c3380/IJT-15-251-g004.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c604/11588195/e0ff6a3bc48c/IJT-15-251-g007.jpg

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