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格雷厄姆-利特尔-皮卡迪-拉叙厄尔综合征及文献综述

Graham-Little Piccardi Lassueur syndrome and review of the literature.

作者信息

Alkhayal Fares A, Alsudairy Fahad, Al Mubarak Luluah, Almohanna Hind M

机构信息

Dermatology and Dermatologic Surgery Department Prince Sultan Military Medical City Riyadh Saudi Arabia.

出版信息

Clin Case Rep. 2021 Sep 5;9(9):e04761. doi: 10.1002/ccr3.4761. eCollection 2021 Sep.

Abstract

Graham-Little Piccardi Lassueur Syndrome (GLPLS) is a rare variant of lichen planopilaris (LPP) which characterized by triad of fibrosing alopecia of the scalp, non-fibrosing alopecia of the axilla and groin, and a follicular spinous papule over the body. LPP is a rare follicular subtype of lichen planus which causes scarring alopecia of scalp, and there are three clinical subtypes of LPP including classic lichen planopilaris, frontal fibrosing alopecia, and GLPLS. Herein, we describe an adult dark-skinned Saudi male with GLPLS who has numerous body follicular papules, complete loss of axillary hair, and partial loss of groin hair in addition to patchy fibrosing alopecia of the scalp. To the best of our knowledge, this is the first reported case of GLPLS in Saudi Arabia.

摘要

格雷厄姆 - 利特尔 - 皮卡迪 - 拉叙厄尔综合征(GLPLS)是扁平苔藓性毛发角化病(LPP)的一种罕见变体,其特征为头皮纤维化性脱发、腋窝和腹股沟非纤维化性脱发以及身体上的毛囊棘状丘疹三联征。LPP是扁平苔藓的一种罕见毛囊亚型,可导致头皮瘢痕性脱发,LPP有三种临床亚型,包括经典扁平苔藓性毛发角化病、额部纤维化性脱发和GLPLS。在此,我们描述了一名患有GLPLS的成年沙特男性,其皮肤黝黑,除头皮有斑片状纤维化性脱发外,身体有大量毛囊丘疹,腋毛完全脱落,腹股沟毛发部分脱落。据我们所知,这是沙特阿拉伯首例报道的GLPLS病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8418680/5cbb519b82cc/CCR3-9-e04761-g005.jpg

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