Abdel Raoof Gehan F, Mahmoud Mourad Rasha M, Mohamed Nagy Hala M
Pharmacognosy Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, Giza, Egypt.
Food Science Department, Faculty of Agriculture, Cairo University, Giza, Egypt.
Chem Biodivers. 2025 Apr;22(4):e202401829. doi: 10.1002/cbdv.202401829. Epub 2024 Dec 11.
The current research was undertaken to investigate the effect of fixed oils of Linum usitatissimum L. (flaxseed), Sesamum indicum L. (sesame), and Salvia hispanica L. (chia) seeds on the chemical profile and weight of the peritoneal fat of rats fed normal (10% fat) or high-fat diet (HFD) (20% fat). Additionally, to analyze the phytoconstituents of these fixed oils, gas chromatography-mass spectrometry (GC/MS) was applied to analyze the experimental oils and the peritoneal fats. Our results revealed a remarkable effect of the experimental oils on the fatty acid profile of peritoneal fat in groups fed on HFD; they limited the increase in saturated fatty acids. Moreover, adding these oils to HFD limited the increase in body weight and decreased the percentage of peritoneal fat. In addition, oleic acid was the major fatty acid in sesame and flaxseed oils (44.2% and 33.69%, respectively). However, linolenic acid was represented as a major fatty acid in chia oil (50.69%). So, we can conclude that sesame, flaxseed, and chia oils can be used as a healthy oil source in food due to their nutritional benefits and remarkable role in controlling the adverse effect of HFD on the quantity and quality of peritoneal fat.
本研究旨在调查亚麻籽（Linum usitatissimum L.）、芝麻（Sesamum indicum L.）和奇亚籽（Salvia hispanica L.）的固定油对喂食正常（10%脂肪）或高脂饮食（HFD，20%脂肪）的大鼠腹膜脂肪的化学组成和重量的影响。此外，为了分析这些固定油的植物成分，采用气相色谱-质谱联用（GC/MS）技术对实验用油和腹膜脂肪进行分析。我们的结果显示，实验用油对喂食HFD的大鼠腹膜脂肪的脂肪酸组成具有显著影响；它们限制了饱和脂肪酸的增加。此外，在HFD中添加这些油可限制体重增加并降低腹膜脂肪百分比。另外，油酸是芝麻油和亚麻籽油中的主要脂肪酸（分别为(44.2%)和(33.69%)）。然而，亚麻酸是奇亚籽油中的主要脂肪酸（(50.69%)）。因此，我们可以得出结论，芝麻油、亚麻籽油和奇亚籽油因其营养益处以及在控制HFD对腹膜脂肪数量和质量的不良影响方面的显著作用，可作为食品中的健康油源。
