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内镜或显微镜下胆脂瘤手术后患者的健康相关生活质量。

Health-related quality of life in patients after endoscopic or microscopic cholesteatoma surgery.

作者信息

Raemy Yannik, Bächinger David, Peter Nicole, Roosli Christof

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zürich, University Zürich, Frauenklinikstrasse 24, 8091, Zürich, Switzerland.

出版信息

Eur Arch Otorhinolaryngol. 2025 May;282(5):2275-2283. doi: 10.1007/s00405-024-09097-8. Epub 2024 Nov 27.

Abstract

PURPOSE

Different surgical techniques exist for treating cholesteatoma, such as microscopical or transcanal endoscopic ear surgery (TEES). This study aimed to compare these two techniques, focusing on quality of life.

METHODS

This retrospective single-center study included 188 patients with cholesteatoma. The primary outcome was the assessment of health-related quality of life (HRQoL) using the Zurich Chronic Middle Ear Inventory (ZCMEI-21) preoperatively, 3 and 12 months postoperatively with regard to surgical technique and intraoperative staging of the cholesteatoma (ChOLE classification). Secondary outcomes included hearing pure tone average of 0.5, 1, 2 and 4 kHz (PTA), complications assessed 3 months postoperatively as well as recidivism within the follow-up time of 1 year postoperatively.

RESULTS

A total of 28 patients underwent TEES and 160 microscopic ear surgery. The ZCMEI-21 total scores preoperatively were not significantly different between the two groups. An improvement in QoL one year postoperatively was observed in both groups to a comparable extent. The ZCMEI-21 decreased significantly (p < 0.01) in both groups. In the TEES group, the cholesteatoma tended to be smaller (lower ChOLE score), PTA was better and complication rate comparable. The number of recidivisms was lower for the TEES group (1 [3.6%] vs. 31 [19.4%]).

CONCLUSION

TEES is a valuable alternative to the traditional microscopic technique, at least for small cholesteatoma, which leads to a comparable improvement in HRQoL as the microscopic technique. The better postoperative hearing and lower rate of recidivism in the TEES group may be related to the smaller extent of the cholesteatoma.

摘要

目的

治疗胆脂瘤存在不同的手术技术,如显微镜下或经耳道内镜耳手术(TEES)。本研究旨在比较这两种技术,重点关注生活质量。

方法

这项回顾性单中心研究纳入了188例胆脂瘤患者。主要结局是使用苏黎世慢性中耳量表(ZCMEI - 21)在术前、术后3个月和12个月评估与健康相关的生活质量(HRQoL),评估内容涉及手术技术和胆脂瘤的术中分期(ChOLE分类)。次要结局包括0.5、1、2和4kHz的纯音平均听阈(PTA)、术后3个月评估的并发症以及术后1年随访期内的复发情况。

结果

共有28例患者接受了TEES,160例接受了显微镜下耳手术。两组术前ZCMEI - 21总分无显著差异。两组术后1年生活质量均有类似程度的改善。两组ZCMEI - 21均显著下降(p < 0.01)。在TEES组中,胆脂瘤往往较小(ChOLE评分较低),PTA较好,并发症发生率相当。TEES组的复发例数较少(1例[3.6%]对31例[19.4%])。

结论

TEES是传统显微镜技术的一种有价值的替代方法,至少对于小型胆脂瘤而言,它能带来与显微镜技术相当的HRQoL改善。TEES组术后听力更好且复发率更低,可能与胆脂瘤范围较小有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fdc/12055632/e76ce359699a/405_2024_9097_Fig1_HTML.jpg

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