Shiroiwa Takeru, Yamamoto Yosuke, Murata Tatsunori, Mulhern Brendan, Bjorner Jakob, Brazier John, Fukuda Takashi, Rowen Donna, Fukuhara Shun-Ichi
Center for Outcomes Research and Economic Evaluation for Health (C2H), National Institute of Public Health, 2-3-6 Minami, Wako, Saitama, 351-0197, Japan.
Department of Healthcare Epidemiology, School of Public Health in the Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Qual Life Res. 2025 Feb;34(2):445-455. doi: 10.1007/s11136-024-03830-w. Epub 2024 Nov 27.
The SF-6D Classification System was recently updated (SF-6Dv2). We performed a valuation survey to construct a value set for the SF-6Dv2 in Japan.
An online discrete choice experiment (DCE) with duration was used to estimate a value set for the SF-6Dv2 for Japan based on public preferences. The target sample number was 3800. Respondents were asked to complete 15 choice tasks. A conditional logit model that estimates interactions between time and each dimension was used to develop the value set.
The collected sample included 3933 respondents for the DCE tasks. The results of all the unconstrained models showed some inconsistencies. In particular, inconsistencies in the two most severe levels of the role limitation (RL) and vitality (VT) dimensions were observed in all models. The number of inconsistencies was smallest in a core model (n = 3) and in a model for core and common health states (n = 2). The physical functioning (PF) and pain (PA) dimensions had the greatest influence on utility at the overall level across all models. RL, VT, and social functioning (SF) had smaller overall impacts on utility. The PF weights for the two most severe levels are much lower than those in the UK and Australia. The Japanese scores tended to be lower compared with the UK SF-6Dv2 scores.
We obtained a value set for Japan (model 5). With the development of this value set, it is now possible to calculate quality-adjusted life years for economic evaluation in Japan when the SF-6Dv2 has been used.
SF-6D分类系统最近进行了更新（SF-6Dv2）。我们开展了一项评估调查，以构建日本SF-6Dv2的价值集。
采用一项包含持续时间的在线离散选择实验（DCE），根据公众偏好估算日本SF-6Dv2的价值集。目标样本数量为3800。要求受访者完成15项选择任务。使用估计时间与各维度之间相互作用的条件logit模型来构建价值集设定。
收集到的样本包括3933名参与DCE任务的受访者。所有无约束模型的结果均显示出一些不一致性。特别是，在所有模型中均观察到角色限制（RL）和活力（VT）维度最严重的两个水平存在不一致性。在核心模型（n = 3）以及核心和常见健康状态模型（n = 2）中，不一致的数量最少。在所有模型的总体水平上，身体功能（PF）和疼痛（PA）维度对效用的影响最大。RL、VT和社会功能（SF）对效用的总体影响较小。两个最严重水平的PF权重远低于英国和澳大利亚的权重。与英国SF-6Dv2分数相比，日本分数往往较低。
我们获得了日本的价值集（模型5）。随着该价值集的构建完成，当使用SF-6Dv2时，现在可以在日本计算用于经济评估的质量调整生命年。
