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巴西东北部皮奥伊州献血者中戊型肝炎病毒感染的血清流行率。

Seroprevalence of hepatitis E virus infection in blood donors from Piauí State, Northeast Brazil.

作者信息

da Silva-Sampaio João Paulo, Sinimbu Raniela Borges, Marques Julia Trece, Neto Abilio Francisco de Oliveira, Villar Livia Melo

机构信息

Fiocruz Piauí, Teresina, PI, Brazil; Fundação Oswaldo Cruz, Instituto Oswaldo Cruz, Laboratório de Hepatites Virais, Rio de Janeiro, RJ, Brazil.

Fundação Oswaldo Cruz, Instituto Oswaldo Cruz, Laboratório de Hepatites Virais, Rio de Janeiro, RJ, Brazil.

出版信息

Braz J Infect Dis. 2025 Jan-Feb;29(1):104466. doi: 10.1016/j.bjid.2024.104466. Epub 2024 Nov 26.

Abstract

A retrospective and cross-sectional study was carried out on blood donors from Piauí State located at Northeastern Brazil to evaluate the prevalence of Hepatitis E Virus (HEV) infection. Serum samples were tested for anti-HEV IgG and IgM using electrochemiluminescence and HEV RNA was tested using real time PCR. A total of 890 individuals were included with median age of 33.4 years and most of them were male and lived at Mid-Northern region of the State. Prevalences of anti-HEV IgG and IgM were 1.35 % and 0.11 %, respectively. None HEV-RNA was detected. This study demonstrated low prevalence of HEV infection in blood donors in this region.

摘要

对位于巴西东北部皮奥伊州的献血者进行了一项回顾性横断面研究,以评估戊型肝炎病毒(HEV)感染的流行情况。使用电化学发光法检测血清样本中的抗HEV IgG和IgM,并使用实时PCR检测HEV RNA。共纳入890人,中位年龄为33.4岁,其中大多数为男性,居住在该州中北部地区。抗HEV IgG和IgM的流行率分别为1.35%和0.11%。未检测到HEV-RNA。这项研究表明该地区献血者中HEV感染的流行率较低。

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