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一名烧伤患者在持续性铜绿假单胞菌感染后,通过使用脱细胞真皮基质模板进行中间伤口覆盖实现肢体挽救。

Limb Salvage through Intermediary Wound Coverage with Acellular Dermal Matrix Template after Persistent Pseudomonas Aeruginosa Infection in a Burn Patient.

作者信息

Gładysz Mateusz, März Vincent, Ruemke Stefan, Rubalskii Evgenii, Vogt Peter Maria, Krezdorn Nicco

机构信息

Burn Center, Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Hanover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.

Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.

出版信息

Eur Burn J. 2022 Jan 12;3(1):27-33. doi: 10.3390/ebj3010004.

Abstract

Secondary infections of skin grafts pose a continuous problem in burn patients, very often leading to loss of transplanted skin grafts and making multiple surgical revisions necessary. We present a case report about persisting Pseudomonas aeruginosa infection in burn patients with known diabetes. The burn wounds in lower extremities required repeated debridements, multiple skin grafting attempts and finally an application of the dermal scaffold NovoSorb BTM. With these measures, we managed to undertake a successful reconstruction of infected burn defects and pre-vent an amputation. We concluded that the NovoSorb BTM could be seen as an additional promising tool in a burn surgery armamentarium. In cases where radical surgical wound decontamination is not possible without risking the loss of the limb, the application of NovoSorb BTM over a contaminated field can win extra time for topical infection treatment and additionally provide an excellent skin grafting ground.

摘要

皮肤移植的继发性感染在烧伤患者中一直是个问题,常常导致移植的皮肤丢失,使得多次手术修复成为必要。我们报告一例已知患有糖尿病的烧伤患者持续感染铜绿假单胞菌的病例。下肢烧伤创面需要反复清创、多次尝试皮肤移植,最终应用了真皮支架NovoSorb BTM。通过这些措施,我们成功地对感染的烧伤缺损进行了重建,避免了截肢。我们得出结论,NovoSorb BTM可被视为烧伤手术器械库中一种有前景的辅助工具。在不冒肢体丢失风险就无法进行彻底手术伤口清创的情况下,在污染区域应用NovoSorb BTM可为局部感染治疗赢得额外时间,并额外提供一个优良的皮肤移植创面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01ef/11575356/30446adec5eb/ebj-03-00004-g001.jpg

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