Africa Unit for Transdisciplinary Health Research (AUTHeR), North-West University, Potchefstroom, South Africa.
University of Cape Town, Cape Town, South Africa.
BMC Cardiovasc Disord. 2024 Nov 27;24(1):685. doi: 10.1186/s12872-024-04248-5.
The aim of this research was to investigate the relationship between socio-economic inequalities and fatal and non-fatal cardiovascular events.
A systematic review of recently published cohort studies and a meta-analysis of relative risk (RR) of low compared with high socio-economic status (SES) in relation to cardiovascular incidence and mortality was conducted. Supplementary evaluations were conducted considering different proxies of SES in relation to different types of cardiovascular disease (CVD).
We identified 17 studies including approximately 26.5 million of participants with more than 900,000 CVD events. We estimated a 50% increased CVD risk for low SES with respect to high SES (RR = 1.49 [95% confidence interval: 1.26, 1.78]). For sex-specific risk, we estimated a 79% increased CVD risk for women of low SES (RR = 1.79 [1.30, 2.46]). In men, the same investigation found a 45% increased CVD risk (RR = 1.45 [1.09, 1.92]). We reported that low education (RR = 1.56 [1.27, 1.91]), increased CVD risk the most, more than low income (RR = 1.38 [1.12, 1.70]).
Although not statistically significant, women of low SES were at higher CVD risk than men. CVD risk was more relevant to educational inequality than economic inequality.
本研究旨在探讨社会经济不平等与致命和非致命心血管事件之间的关系。
对最近发表的队列研究进行系统评价，并对低社会经济地位（SES）与心血管发病率和死亡率的相对风险（RR）进行荟萃分析。考虑到不同类型心血管疾病（CVD）与 SES 不同的代理变量，进行了补充评估。
我们确定了 17 项研究，包括约 2650 万参与者，其中有超过 90 万例 CVD 事件。我们估计 SES 低的 CVD 风险增加了 50%（RR=1.49[95%置信区间：1.26，1.78]）。对于性别特异性风险，我们估计 SES 低的女性 CVD 风险增加了 79%（RR=1.79[1.30，2.46]）。在男性中，同样的调查发现 CVD 风险增加了 45%（RR=1.45[1.09，1.92]）。我们报告说，低教育（RR=1.56[1.27,1.91]）增加 CVD 风险的程度超过了低收入（RR=1.38[1.12,1.70]）。
尽管没有统计学意义，但 SES 低的女性比男性患 CVD 的风险更高。CVD 风险与教育不平等的关系比经济不平等更密切。
