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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Aoi W, Seto S, Doi Y, Murayama M, Tasaki S, Suzuki S, Kuramochi M, Hashiba K

Clin Sci (Lond). 1979 Dec;57 Suppl 5:101s-103s. doi: 10.1042/cs057101s.

Active and inactive renin were assayed in plasma of the renal veins and the inferior vena cava below the kidney in eight patients with hypertension and unilateral renal abnormalities, 20 min after the patients had resumed the upright position. 2. The concentration of active renin on the affected side was significantly higher than that on the non-affected side. The concentration of inactive renin on the affected side was significantly lower than that on the non-affected side and in the inferior vena cava. 3. These findings suggest either that the affected kidney mainly secretes active renin, which is then converted into inactive renin in the extrarenal circulation, or that the affected kidney activates inactive renin.

对8例患有高血压和单侧肾脏异常的患者，在其恢复直立姿势20分钟后，测定肾静脉血浆以及肾下方下腔静脉血浆中的活性肾素和非活性肾素。2. 患侧活性肾素浓度显著高于未患侧。患侧非活性肾素浓度显著低于未患侧以及下腔静脉中的浓度。3. 这些发现表明，要么患肾主要分泌活性肾素，然后在肾外循环中转化为非活性肾素，要么患肾激活非活性肾素。

Aoi W, Seto S, Doi Y, Murayama M, Tasaki S, Suzuki S, Kuramochi M, Hashiba K

Clin Sci (Lond). 1979 Dec;57 Suppl 5:101s-103s. doi: 10.1042/cs057101s.

Active and inactive renin were assayed in plasma of the renal veins and the inferior vena cava below the kidney in eight patients with hypertension and unilateral renal abnormalities, 20 min after the patients had resumed the upright position. 2. The concentration of active renin on the affected side was significantly higher than that on the non-affected side. The concentration of inactive renin on the affected side was significantly lower than that on the non-affected side and in the inferior vena cava. 3. These findings suggest either that the affected kidney mainly secretes active renin, which is then converted into inactive renin in the extrarenal circulation, or that the affected kidney activates inactive renin.

对8例患有高血压和单侧肾脏异常的患者，在其恢复直立姿势20分钟后，测定肾静脉血浆以及肾下方下腔静脉血浆中的活性肾素和非活性肾素。2. 患侧活性肾素浓度显著高于未患侧。患侧非活性肾素浓度显著低于未患侧以及下腔静脉中的浓度。3. 这些发现表明，要么患肾主要分泌活性肾素，然后在肾外循环中转化为非活性肾素，要么患肾激活非活性肾素。