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采用 EORTC 30 方案评估软组织肉瘤患者手术治疗后的生活质量。

Assessment of quality of life using the EORTC 30 protocol in patients with soft tissue sarcoma undergoing surgical treatment.

机构信息

- Universidade Estadual de Ponta Grossa, Departamento de Cirurgia Geral - Ponta Grossa - PR - Brasil.

- Faculdade Evangélica de Medicina Mackenzie do Paraná, Departamento de Oncologia - Curitiba - PR - Brasil.

出版信息

Rev Col Bras Cir. 2024 Nov 25;51:e20243766. doi: 10.1590/0100-6991e-20243766-en. eCollection 2024.

DOI:10.1590/0100-6991e-20243766-en
PMID:39607184
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11548874/
Abstract

OBJECTIVE

To evaluate the quality of life among patients with Soft Tissue Sarcomas treated at the Evangelic Mackenzie Hospital (HUEM) from 2018 to 2024 and undergoing surgical treatment.

MATERIAL AND METHODS

descriptive and cross-sectional analysis of 23 patients with soft tissue neoplasia who underwent surgery and whether they underwent neoadjuvant or adjuvant clinical treatments. Epidemiological, clinical, and pathological data were considered. The EORTC 30 protocol was the instrument used for assessing the patients' quality of life.

RESULTS

the main cases were located at extremity in females. Mean age at diagnosis was 47 years. All patients were symptomatic at diagnosis, with pain and a palpable mass being the most prevalent symptom and clinical sign, respectively. The mean time from the onset of symptoms to the date of diagnosis was 9 months. The mean tumor size was 11.68cm. Considering the functional scale, the items physical functioning, role performance and social function were the most affected in the assessment of quality of life. Fatigue and loss of appetite were the most common sign and symptom, respectively. A global measure of quality of life achieved high rates when 50% of patients rated as excellent.

CONCLUSION

Continuous and multidisciplinary oncological care provided to the patient allows for better symptom control, resulting in higher quality of life, which positively impacts the patient's adherence to treatment, their progression, and possibly their survival.

摘要

目的

评估 2018 年至 2024 年在 Evangelic Mackenzie 医院(HUEM)接受手术治疗的软组织肉瘤患者的生活质量,这些患者接受了手术治疗且接受了新辅助或辅助临床治疗。

材料和方法

对 23 名患有软组织肿瘤且接受手术的患者进行描述性和横断面分析,无论他们是否接受新辅助或辅助临床治疗。考虑了流行病学、临床和病理数据。EORTC 30 方案是用于评估患者生活质量的工具。

结果

主要病例位于女性的四肢。诊断时的平均年龄为 47 岁。所有患者在诊断时均有症状,疼痛和可触及的肿块分别是最常见的症状和临床体征。从症状出现到诊断的平均时间为 9 个月。肿瘤的平均大小为 11.68cm。考虑功能量表,在生活质量评估中,身体功能、角色表现和社会功能这三个项目受到的影响最大。疲劳和食欲不振分别是最常见的症状和体征。当 50%的患者评为优秀时,整体生活质量评估达到了较高的水平。

结论

为患者提供持续的多学科肿瘤治疗可以更好地控制症状,从而提高生活质量,这对患者对治疗的依从性、疾病进展和生存情况产生积极影响。

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Extremities Soft Tissue Sarcomas, more Common and as Dangerous as Bone Sarcomas.肢体软组织肉瘤比骨肉瘤更常见且同样危险。
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