Department of Medical Psychology and Medical Sociology, University of Leipzig, Leipzig, Germany.
J Gynecol Oncol. 2013 Jul;24(3):280-6. doi: 10.3802/jgo.2013.24.3.280. Epub 2013 Jul 4.
The objective of this study is to examine the course of fatigue in female cancer patients during the first months after treatment.
We examined a sample of 110 patients suffering from gynecological or breast cancer. Fatigue was assessed with two questionnaires, the Multidimensional Fatigue Inventory (MFI) and the fatigue scale of the quality of life questionnaire European Organisation for Research and Treatment of Cancer (EORTC QLQ-C30). Participants were tested during their stay in the hospital (t1), two weeks after discharge (t2), and three months after discharge (t3).
Fatigue in the patients' sample was markedly higher than the general population reference values. At t1, the effect sizes are d=0.81 (MFI) and d=1.21 (EORTC QLQ-C30 fatigue scale). Age and tumor stage had no significant influence on fatigue, but patients with a long time since diagnosis had higher fatigue levels than patients with a shorter time since diagnosis. From t1 to t3, fatigue mean scores decreased. The correlations between the t1 and the t3 fatigue scores were weak, with correlation coefficients of only about 0.30.
Though the mean scores of fatigue, averaged across all patients, decreased over the first three months, the individual courses could not be predicted from the t1 score.
本研究旨在探讨女性癌症患者在治疗后最初几个月内的疲劳进程。
我们检查了 110 名患有妇科或乳腺癌的患者样本。使用多维疲劳量表（MFI）和欧洲癌症研究与治疗组织生活质量问卷（EORTC QLQ-C30）的疲劳量表评估疲劳。参与者在住院期间（t1）、出院后两周（t2）和出院后三个月（t3）接受测试。
患者样本中的疲劳明显高于一般人群的参考值。在 t1 时，效应大小为 d=0.81（MFI）和 d=1.21（EORTC QLQ-C30 疲劳量表）。年龄和肿瘤分期对疲劳没有显著影响，但诊断时间较长的患者比诊断时间较短的患者疲劳程度更高。从 t1 到 t3，疲劳平均得分下降。t1 和 t3 疲劳得分之间的相关性较弱，相关系数仅约为 0.30。
尽管所有患者的平均疲劳得分在头三个月内有所下降，但从 t1 得分无法预测个体的疲劳进程。
