Language and Cognitive Impairments in Multiple Sclerosis: a Comparative Study of RRMS and SPMS Patients.
作者信息
Martzoukou Maria, Nousia Anastasia, Messinis Lambros, Konstantopoulos Kostas, Nasios Grigorios
机构信息
Lab of Cognitive Neuroscience, School of Psychology, Aristotle University of Thessaloniki, University Campus, Thessaloniki, 54124, Greece.
Department of Speech and Language Therapy, University of Peloponnese, Antikalamos, Kalamata, 24100, Greece.
出版信息
Arch Clin Neuropsychol. 2025 May 21;40(4):775-782. doi: 10.1093/arclin/acae110.
OBJECTIVE
Previous studies have reported that patients with Multiple Sclerosis (MS) face cognitive difficulties. Much less, however, is known about their language abilities. The present study aims to provide a clear view of the language abilities of adults with MS, considering their cognitive skills and the type of the disorder.
METHOD
Specifically, 20 patients with Relapsing-Remitting MS, 17 patients with Secondary Progressive MS, and two healthy control groups demographically matched with the clinical groups, took part in the study. Their language abilities were examined using the Adult Language Abilities Test, which explores morpho-syntactic and semantic phenomena of the Greek language in both comprehension and production modes.
RESULTS
Our results did not reveal statistically significant differences between the two clinical groups on any cognitive or language subtest. Both groups, however, performed poorer than the control groups in producing the correct form of verbs, possessive and weak personal pronouns, and in comprehending relative and passive clauses. Participants' performance in morphosyntax was found to be related to their processing speed.
CONCLUSION
Mapping the cognitive and language abilities of patients with MS is crucial for designing effective targeted interventions, which can help them adopt strategies to manage their specific cognitive and language symptoms.
Zotero 插件