Ram Shai, Shalev-Ram Hila, Alon Shira, Shapira Ziv, Berkovitz-Shperling Roza, Johansson-Lipinski Margaret, Yogev Yariv, Many Ariel
Lis Hospital for Women, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Gynecol Obstet Invest. 2025;90(3):226-233. doi: 10.1159/000542825. Epub 2024 Nov 28.
The increasing rate of cesarean sections (CSs) raises concerns over severe intra-abdominal adhesions, which are associated with numerous complications. We aimed to identify risk factors and predictive tools for severe adhesions.
A prospective study was conducted. Participants/Materials: Women with at least one prior CS were evaluated.
The study was conducted at a tertiary medical center from January to July 2021.
Surgeons assessed adhesions at four anatomical sites, scoring them from 0 (none) to 2 (dense), with a total possible score of 0-8. Severe adhesions were defined as a score of ≥5. Risk factors were analyzed using logistic regression to create a prediction model.
Overall, 341 women were included in the study. Significant predictors included the number of previous CS, maternal body mass index, maternal morbidity at the time of the previous CS, and operation time. The model predicted severe adhesions with 79.1% accuracy, a positive predictive value of 68.4%, and a negative predictive value of 79.5%.
Few risk factors, such as surgical history beyond cesarean sections, endometriosis, and pelvic inflammatory disease were not available. Additionally, the sample size of 341 women, while substantial, may limit the identification of further risk factors and the precision of the predictive model.
The severity of most cases of post-CS adhesions can be predicted by a model which considers common risk factors.
剖宫产率的不断上升引发了对严重腹腔内粘连的担忧,这种粘连与多种并发症相关。我们旨在确定严重粘连的风险因素和预测工具。
进行了一项前瞻性研究。参与者/材料:对至少有一次既往剖宫产史的女性进行评估。
该研究于2021年1月至7月在一家三级医疗中心进行。
外科医生评估四个解剖部位的粘连情况,从0(无)到2(致密)进行评分,总评分范围为0 - 8分。严重粘连定义为评分≥5分。使用逻辑回归分析风险因素以创建预测模型。
总体而言,341名女性纳入研究。显著的预测因素包括既往剖宫产次数、产妇体重指数、既往剖宫产时的产妇发病率以及手术时间。该模型预测严重粘连的准确率为79.1%,阳性预测值为68.4%,阴性预测值为79.5%。
一些风险因素,如剖宫产以外的手术史、子宫内膜异位症和盆腔炎等未纳入分析。此外,341名女性的样本量虽然可观,但可能会限制进一步风险因素的识别以及预测模型的精度。
通过考虑常见风险因素的模型可以预测大多数剖宫产术后粘连病例的严重程度。