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肝细胞癌的诊断和分期:当前实践综述。

The Diagnosis and Staging of Hepatocellular Carcinoma: A Review of Current Practices.

机构信息

Division of Gastroenterology and Hepatology, University of Washington Medical Center, 1536 North 115th Street, Suite 105, Box 358811, Seattle, WA 98133, USA.

Division of Gastroenterology and Hepatology, University of Washington Medical Center, 1536 North 115th Street, Suite 105, Box 358811, Seattle, WA 98133, USA.

出版信息

Clin Liver Dis. 2025 Feb;29(1):33-48. doi: 10.1016/j.cld.2024.08.007. Epub 2024 Oct 28.

Abstract

Promoting the early detection and diagnosis of hepatocellular carcinoma (HCC) is a critical strategy to improve patient outcomes as this can lead to greater access to curative treatments. This review highlights the diagnostic tests for HCC, including the use of the Liver Imaging Reporting and Data System systems and histopathology. Staging is essential for informing prognosis and guiding treatment decisions; this review also covers a widely used and well-validated staging system called the Barcelona-Clinic Liver Cancer (BCLC) algorithm. The BCLC incorporates tumor status, liver function, and patient performance to stage patients with newly diagnosed HCC.

摘要

促进肝细胞癌(HCC)的早期发现和诊断是改善患者预后的关键策略,因为这可以使更多患者获得根治性治疗。本文综述了 HCC 的诊断检测方法,包括使用肝脏影像报告和数据系统以及组织病理学。分期对于告知预后和指导治疗决策至关重要;本文还介绍了一种广泛使用且经过良好验证的分期系统,即巴塞罗那临床肝癌(BCLC)算法。BCLC 结合了肿瘤状态、肝功能和患者体能状况对新诊断 HCC 患者进行分期。

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