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新冠疫情早期阶段新冠病毒感染状况与经济成本之间的关联:来自英国症状监测数字调查的证据

The Association between COVID-19 Status and Economic Costs in the Early Stages of the COVID-19 Pandemic: Evidence from a UK Symptom Surveillance Digital Survey.

作者信息

Kim Sung Wook, Alacevich Caterina, Nicodemo Catia, Wittenberg Raphael, de Lusignan Simon, Petrou Stavros

机构信息

Nuffield Department of Primary Care Health Sciences, University of Oxford, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, England, UK.

University of Florida, Gainesville, USA.

出版信息

Pharmacoecon Open. 2025 Mar;9(2):231-245. doi: 10.1007/s41669-024-00544-0. Epub 2024 Nov 28.

Abstract

INTRODUCTION

In the absence of a vaccination programme, the coronavirus disease 2019 (COVID-19) pandemic had substantial impacts on population health and wellbeing and health care services. We explored the association between COVID-19 status, sociodemographic, socioeconomic and clinical factors and economic costs during the second wave of the COVID-19 pandemic.

DATA

The study used patient-reported digital survey and symptom surveillance data collected between July and December 2020, in collaboration with a primary care computerised medical record system supplier, EMIS Health, in the UK. The study included 11,534 participants.

METHODS

Generalised linear models (GLM) and two-part regression models were used to estimate factors associated with economic costs (£sterling, 2022 prices) estimated from two perspectives: (i) a UK National Health Service (NHS) and personal social services (PSS) perspective and (ii) a societal perspective.

RESULTS

Experience of the onset of COVID-19 symptoms started more than 3 months ago was associated with significantly higher NHS and PSS costs (GLM: £319.8, two-part: £171.7) (p < 0.001) and societal costs (GLM: £776.9, two-part: £675.6) (p < 0.001) in both models. A positive test result within the previous 14 days was associated with significantly higher NHS and PSS costs (two-part: £389.1) (p < 0.05) and societal costs (GLM: £470.7, two-part: £439.2) (p < 0.01). Age between 31 and 55 years was associated with significantly higher societal costs than age between 16 and 30 years.

CONCLUSION

This study identifies and quantifies factors associated with the economic costs incurred during the second wave of the COVID-19 pandemic in the UK. The results of our study can inform cross-country comparisons and other cost comparisons.

摘要

引言

在没有疫苗接种计划的情况下,2019冠状病毒病(COVID-19)大流行对人群健康、福祉以及医疗服务产生了重大影响。我们探讨了在COVID-19大流行第二波期间,COVID-19状态、社会人口统计学、社会经济和临床因素与经济成本之间的关联。

数据

该研究使用了患者报告的数字调查和症状监测数据,这些数据于2020年7月至12月期间收集,是与英国一家初级保健计算机化医疗记录系统供应商EMIS Health合作开展的。该研究纳入了11534名参与者。

方法

采用广义线性模型(GLM)和两部分回归模型,从两个角度估计与经济成本(2022年价格,英镑)相关的因素:(i)英国国家医疗服务体系(NHS)和个人社会服务(PSS)角度;(ii)社会角度。

结果

在两种模型中,COVID-19症状发作超过3个月之前的经历与NHS和PSS成本显著更高(GLM:319.8英镑,两部分模型:171.7英镑)(p<0.001)以及社会成本显著更高(GLM:776.9英镑,两部分模型:675.6英镑)(p<0.001)相关。过去14天内检测呈阳性与NHS和PSS成本显著更高(两部分模型:389.1英镑)(p<0.05)以及社会成本显著更高(GLM:470.7英镑,两部分模型:439.2英镑)(p<0.01)相关。31至55岁的年龄组与16至30岁的年龄组相比,社会成本显著更高。

结论

本研究确定并量化了与英国COVID-19大流行第二波期间产生的经济成本相关的因素。我们的研究结果可为跨国比较和其他成本比较提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210c/11865407/69cfb3329be6/41669_2024_544_Fig1_HTML.jpg

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