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变应性鼻炎管理:意大利儿科过敏和免疫学会(SIAIP)推动的 Delphi 共识。

Allergic rhinitis management: a Delphi Consensus promoted by the Italian Society of Pediatric Allergy and Immunology (SIAIP).

机构信息

Department of Woman, Child and General and Specialized Surgery, University of Campania Luigi Vanvitelli, Naples, Italy.

Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

出版信息

Ital J Pediatr. 2024 Nov 28;50(1):254. doi: 10.1186/s13052-024-01824-5.

Abstract

Allergic rhinitis (AR) is the most frequent IgE-mediated disease, mainly in children and adolescents. Management of AR in the pediatric age may be heterogeneous, and the available guidelines do not adequately consider this issue. As a result, the Italian Society of Pediatric Allergy and Immunology (SIAIP) promoted a Delphi Consensus to define and evaluate the most relevant aspects of AR management in the pediatric setting in Italy. A qualified board of experts prepared a list of statements that a panel of Italian experts voted on using a web platform. Forty-two pediatricians participated. The results showed that all statements had consensus (> 80% of scores 4 + 5). In particular, there was awareness that AR is a type 2 inflammatory disease requiring adequate treatment. Topical drugs should be preferred, as they are better with cycles. Combined antihistamine/corticosteroid is also considered effective and safe in adolescents. In conclusion, AR deserves adequate attention and care. Current medications are safe and effective; treatment should be addressed to dampen type 2 inflammation and relieve complaints.

摘要

变应性鼻炎(AR)是最常见的 IgE 介导疾病,主要发生在儿童和青少年中。儿童时期 AR 的管理可能存在异质性,并且现有的指南没有充分考虑到这个问题。因此,意大利儿科过敏和免疫学学会(SIAIP)发起了一项 Delphi 共识,以定义和评估意大利儿科 AR 管理中最相关的方面。一组合格的专家编写了一份陈述清单,供意大利专家组使用网络平台进行投票。共有 42 名儿科医生参与。结果表明,所有的陈述都达成了共识(>80%的评分在 4+5 之间)。特别是,人们认识到 AR 是一种需要适当治疗的 2 型炎症性疾病。局部药物应优先使用,因为它们的效果更好。在青少年中,联合抗组胺药/皮质类固醇也被认为是有效和安全的。总之,AR 需要得到足够的重视和护理。目前的药物是安全有效的;治疗应针对抑制 2 型炎症和缓解症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a440/11603965/e2409ba40c2e/13052_2024_1824_Fig1_HTML.jpg

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