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马来西亚老年人中与痴呆症相关的因素:来自国民健康与发病率调查的结果。

Factors associated with dementia among older people in Malaysia: Findings from National Health and Morbidity Survey.

作者信息

Nasaruddin Nur Hamizah, Ganapathy Shubash Shander, Tham Sin Wan

机构信息

Institute for Public Health, National Institutes of Health, Ministry of Health, Shah Alam, Malaysia.

出版信息

Australas J Ageing. 2025 Mar;44(1):e13392. doi: 10.1111/ajag.13392. Epub 2024 Nov 29.

DOI:10.1111/ajag.13392
PMID:39611244
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11752841/
Abstract

OBJECTIVE

To identify factors associated with dementia among older people in Malaysia.

METHODS

This study used data from a nationwide cross-sectional survey in Malaysia. Participants involved were older people aged 60 years and above. Data collected were on dementia risk factors as well as dementia screening. Dementia screening was done using the Identification and Intervention for Dementia in Elderly Africans cognitive screening tool. Univariate analysis and multiple logistic regression were carried out to determine the factors associated with dementia.

RESULTS

There were 3774 participants involved in this study. Multiple logistic regression showed factors associated with dementia among older people were those aged 70 years and above, Indian ethnic group, being single, primary or no formal education, as well as those with hypertension. Interestingly, our findings also showed that older people with hypercholesterolemia have lower odds of having dementia.

CONCLUSIONS

Multiple factors were associated with dementia in Malaysia, highlighting the need to implement multiple interventions strategies, by taking a lifetime approach emphasizing education, physical as well as social aspects.

摘要

目的

确定马来西亚老年人中与痴呆症相关的因素。

方法

本研究使用了马来西亚全国性横断面调查的数据。参与对象为60岁及以上的老年人。收集的数据包括痴呆症风险因素以及痴呆症筛查。痴呆症筛查采用针对非洲裔老年人的痴呆症识别与干预认知筛查工具进行。进行单因素分析和多因素逻辑回归以确定与痴呆症相关的因素。

结果

本研究共有3774名参与者。多因素逻辑回归显示,老年人中与痴呆症相关的因素包括70岁及以上、印度族裔、单身、小学或未接受过正规教育以及患有高血压。有趣的是,我们的研究结果还表明,患有高胆固醇血症的老年人患痴呆症的几率较低。

结论

在马来西亚,多种因素与痴呆症相关,这凸显了通过采取强调教育、身体和社会方面的终身方法来实施多种干预策略的必要性。

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Association between cholesterol levels and dementia risk according to the presence of diabetes and statin use: a nationwide cohort study.根据是否患有糖尿病和使用他汀类药物,胆固醇水平与痴呆风险之间的关系:一项全国性队列研究。
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The prevalence of hypertension among Malaysian adults and its associated risk factors: data from Malaysian Community Salt Study (MyCoSS).马来西亚成年人高血压的患病率及其相关危险因素:来自马来西亚社区盐研究(MyCoSS)的数据。
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Hypertension and Hypercholesterolemia Modify Dementia Risk in Relation to APOEɛ4 Status.高血压和高胆固醇血症改变 APOEɛ4 状态与痴呆风险的关系。
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Prevalence of dementia and quality of life of caregivers of people living with dementia in Malaysia.马来西亚痴呆症患者和其照料者的痴呆症患病率和生活质量。
Geriatr Gerontol Int. 2020 Dec;20 Suppl 2:16-20. doi: 10.1111/ggi.14031.
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How can dementia and disability be prevented in older adults: where are we today and where are we going?如何预防老年人的痴呆和残疾:我们今天在哪里,我们要去哪里?
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Prevalence, risk factors, and management of dementia and mild cognitive impairment in adults aged 60 years or older in China: a cross-sectional study.中国 60 岁及以上成年人痴呆和轻度认知障碍的患病率、风险因素和管理:一项横断面研究。
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