Hempel V, Krebs P
Reg Anaesth. 1986 Jan;9(1):22-5.
A mixture of 0.2% bupivacaine and 0.75% mepivacaine was employed for brachial plexus block in 20 patients scheduled for surgery of the forearm-hand-region. Volumes of 40-60 ml were given. The spread of motor and sensory block was monitored during 80 min. The first postoperative pain sensation was reported about seven hours after injection of the local anaesthetic. The results are compared to those obtained with 1% plain mepivacaine. The spread of the block was slightly slower after the mixture than after plain mepivacaine. Blood levels after the mixture showed a maximum 30 min after injection.
对20例计划进行前臂-手部区域手术的患者，采用0.2%布比卡因与0.75%甲哌卡因的混合液进行臂丛神经阻滞。给药量为40 - 60毫升。在80分钟内监测运动和感觉阻滞的范围。首次术后疼痛感觉在注射局部麻醉剂约7小时后出现。将结果与使用1%单纯甲哌卡因所获得的结果进行比较。混合液注射后阻滞范围的扩散比单纯甲哌卡因稍慢。混合液注射后30分钟血药浓度达到最高。
