Dreesen H, Büttner J, Klose R
Reg Anaesth. 1986 Apr;9(2):42-5.
The latency period and spread of axillary plexus block using 40 ml mepivacaine carbonate (1% solution) or mepivacaine hydrochloride was studied in thirty patients scheduled for surgery of the hand-forearm region. The sensory block of the nervus axillaris, musculocutaneus, radialis, medianus, ulnaris and cutaneus brachii medialis was recorded using the pin prick test every 4 min after injection and the motor block was assessed by testing the strength of the corresponding muscles. The only significant difference between the two local anaesthetic solutions was a few more frequent and faster anaesthesia of the nervus musculocutaneus after 16, 20 and 24 min. A comparison between the serum levels of the first five patients of each group showed a faster increase and a higher level after the injection of carbonated mepivacaine. Carbonated mepivacaine doesn't have any practical advantage for axillary plexus block.
在30例计划进行手-前臂区域手术的患者中，研究了使用40毫升碳酸甲哌卡因（1%溶液）或盐酸甲哌卡因进行腋路臂丛阻滞的潜伏期和扩散情况。注射后每4分钟使用针刺试验记录腋神经、肌皮神经、桡神经、正中神经、尺神经和臂内侧皮神经的感觉阻滞情况，并通过测试相应肌肉的力量评估运动阻滞情况。两种局部麻醉溶液之间唯一显著的差异是在16、20和24分钟后，肌皮神经的麻醉更频繁且起效更快。每组前5名患者的血清水平比较显示，注射碳酸甲哌卡因后升高更快且水平更高。碳酸甲哌卡因在腋路臂丛阻滞方面没有任何实际优势。
