Bradley Heather, Luisi Nicole, Carter Anastasia, Pigott Terri D, Abramovitz Daniela, Allen Sean T, Asher Alice, Austin Chelsea, Bartholomew Tyler S, Baum Marianna, Board Amy, Boodram Basmattee, Borquez Annick, Brookmeyer Kathryn A, Buchacz Kate, Burnett Janet, Cooper Hannah L F, Crepaz Nicole, Debeck Kora, Feinberg Judith, Fong Chunki, Freeman Edward, Furukawa Nathan Woo, Genberg Becky, Gorbach Pamina, Hagan Holly, Hayashi Kanna, Huriaux Emalie, Hurley Hermione, Keruly Jeanne, Kristensen Kathleen, Lai Shenghan, Martin Natasha K, Mateu-Gelabert Pedro, Mcclain Gregory M, Mehta Shruti, Mok Wing Yin, Reynoso Marley, Strathdee Steffanie, Torigian Nicole, Weng Chenziheng Allen, Westergaard Ryan, Young April, Des Jarlais Don C
Emory University Rollins School of Public Health, Department of Epidemiology.
Georgia State University School of Public Health, Department of Population Health Sciences, Atlanta, GA.
AIDS. 2025 Mar 15;39(4):434-447. doi: 10.1097/QAD.0000000000004076. Epub 2024 Dec 23.
Using an innovative data sharing model, we assessed the impacts of the COVID-19 pandemic on the health of people who inject drugs (PWID).
The PWID Data Collaborative was established in 2021 to promote data sharing across PWID studies in North America. Contributing studies submitted aggregate data on 23 standardized indicators during four time periods: prepandemic (March 2019 to February 2020), early-pandemic (March 2020 to February 2021), mid-pandemic (March 2021 to February 2022), and late pandemic (March 2022 to February 2023).
We present study-specific and meta-analyzed estimates for the percentage of PWID who took medications for opioid use disorder, received substance use treatment, shared syringes or injection equipment, had a mental health condition, had been incarcerated, or had experienced houselessness. To examine change over time across indicators, we fit a random effects meta-regression model to prevalence estimates using time as a moderator.
Thirteen studies contributed estimates to the Data Collaborative on these indicators, representing 6213 PWID interviews. We observed minimal change across prevalence of the six indicators between the prepandemic (March 2019 to February 2020) and three subsequent time periods, overall or within individual studies. Considerable heterogeneity was observed across study-specific and time-specific estimates.
Limited pandemic-related change observed in indicators of PWID health is likely a result of policy and supportive service-related changes and may also reflect resilience among service providers and PWID themselves. The Data Collaborative is an unprecedented data sharing model with potential to greatly improve the quality and timeliness of data on the health of PWID.
我们采用一种创新的数据共享模式,评估了新冠疫情对注射吸毒者健康的影响。
注射吸毒者数据协作组织于2021年成立,以促进北美地区注射吸毒者研究之间的数据共享。参与研究的机构在四个时间段提交了关于23项标准化指标的汇总数据:疫情前(2019年3月至2020年2月)、疫情早期(2020年3月至2021年2月)、疫情中期(2021年3月至2022年2月)和疫情后期(2022年3月至2023年2月)。
我们给出了针对注射吸毒者服用阿片类物质使用障碍药物、接受物质使用治疗、共用注射器或注射设备、患有精神疾病、被监禁或经历无家可归情况的百分比的具体研究估计值和荟萃分析估计值。为了研究各指标随时间的变化,我们将时间作为调节变量,对患病率估计值拟合了随机效应荟萃回归模型。
13项研究为该数据协作组织提供了这些指标的估计值,代表了6213次对注射吸毒者的访谈。我们观察到,在疫情前(2019年3月至2020年2月)与随后三个时间段之间,这六项指标的患病率总体上或在个别研究中变化极小。在具体研究和特定时间的估计值中观察到了相当大的异质性。
注射吸毒者健康指标中观察到的与疫情相关的变化有限,可能是政策和支持性服务相关变化的结果,也可能反映了服务提供者和注射吸毒者自身的复原力。数据协作组织是一种前所未有的数据共享模式,有潜力极大地提高注射吸毒者健康数据的质量和及时性。