Hanoi Medical University, 1 Ton That Tung street, Dong Da, Hanoi, Vietnam.
Respiratory Center, Bach Mai Hospital, Hanoi, Vietnam.
Sleep Breath. 2024 Nov 30;29(1):34. doi: 10.1007/s11325-024-03165-3.
Crouzon syndrome (CS) is a hereditary disorder characterized by deformities of the face and skull brought on by syndromic craniosynostosis or the premature fusion of coronal sutures. Pediatric patients with Crouzon syndrome have a high likelihood of developing obstructive sleep apnea (OSAS), primarily due to skeletal hypoplasia and facial dysmorphism. Treatment of OSAS in patients with Crouzon syndrome requires multidisciplinary and sequential treatment planning because Crouzon syndrome often has different phenotypes with varying severity in OSA and facial dysmorphism. In this clinical case, we describe the first case of a child with Crouzon syndrome with sleep apnea who was treated with positive pressure ventilation in Vietnam.
克鲁宗综合征（CS）是一种遗传性疾病，其特征为颅缝早闭或冠状缝过早融合导致的面部和颅骨畸形。患有克鲁宗综合征的儿科患者发生阻塞性睡眠呼吸暂停（OSAS）的可能性较高，主要是由于骨骼发育不良和面部畸形。由于克鲁宗综合征在 OSA 和面部畸形方面具有不同的表型，且严重程度各异，因此患有克鲁宗综合征的 OSAS 患者的治疗需要多学科和序贯治疗计划。在本临床病例中，我们描述了越南首例患有睡眠呼吸暂停的克鲁宗综合征患儿经正压通气治疗的病例。
