Massalha Hazar, Menascu Shay, Alster Sapir Dreyer, Aloni Roy, Kalron Alon
Department of Physical Therapy, School of Health Professions, Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel.
Multiple Sclerosis Center, Sheba Medical Center, Tel Hashomer, Israel.
Mult Scler Relat Disord. 2025 Jan;93:106189. doi: 10.1016/j.msard.2024.106189. Epub 2024 Nov 26.
A common tool used to measure cognitive reserve is the Cognitive Reserve Index questionnaire (CRIq). In the present study, we aimed to adapt and determine the psychometric properties (validity and intra-rater test-retest reliability) of the Hebrew version of the CRIq in a cohort of people with multiple sclerosis (pwMS).
Fifty pwMS (30 women aged 48.3 (SD=10.2)) completed the CRIq and the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS), which were used for validation. Secondary outcome measures included the evaluation of depression, anxiety, and perceived fatigue. Twenty-five (of the 50) pwMS were randomly selected and participated in the CRIq intra-rater test-retest reproducibility study based on a 7-12-day interval between tests.
The mean CRIq total was 101.8 (S.D.=13.04), which is considered at the medium level. The CRIq section scores were at a similar medium level. According to Pearson's Rho correlation analysis, the CRIq total score and sections of education, work, and leisure were significantly correlated at a medium level (Rho ranging between 0.282 to 0.415) with the SDMT score, a measurement of cognitive information processing speed. The intraclass correlation coefficient (ICC) values of the CRIq total and CRIq sections ranged between 0.942 to 0.998, indicating a strong correlation.
The Hebrew version of the CRIq is a reliable and valid tool for assessing cognitive reserve in pwMS, hence enabling clinicians and researchers to effectively monitor cognitive reserve in this population.
认知储备指数问卷（CRIq）是一种常用的测量认知储备的工具。在本研究中，我们旨在对CRIq希伯来语版本进行改编，并确定其在多发性硬化症患者（pwMS）队列中的心理测量特性（效度和评分者内重测信度）。
50名pwMS患者（30名女性，年龄48.3岁（标准差=10.2））完成了用于验证的CRIq和简短国际多发性硬化症认知评估（BICAMS）。次要结局指标包括对抑郁、焦虑和感知疲劳的评估。从50名pwMS患者中随机选取25名，基于两次测试间隔7至12天参与CRIq评分者内重测信度再现性研究。
CRIq总分的平均值为101.8（标准差=13.04），处于中等水平。CRIq各部分得分也处于类似的中等水平。根据Pearson相关分析，CRIq总分以及教育、工作和休闲部分与认知信息处理速度的测量指标SDMT得分在中等水平上显著相关（相关系数Rho在0.282至0.415之间）。CRIq总分和各部分的组内相关系数（ICC）值在0.942至0.998之间，表明相关性很强。
CRIq希伯来语版本是评估pwMS认知储备的可靠且有效的工具，从而使临床医生和研究人员能够有效地监测该人群的认知储备。
