Terblanche A P, Falkson G
S Afr Med J. 1986 Mar 15;69(6):358-63.
Ninety-five patients with advanced non-Hodgkin's lymphoma (NHL) were studied to evaluate parameters affecting their survival. The median survival time was 52 months (range 3-107 months). The log-rank test was used to analyse the data. Favourable parameters that significantly influenced actuarial survival were nodular histology (P = 0.01), age less than 50 years (P = 0.002), good performance status (P = 0.006), and normal serum lactate dehydrogenase, SGOT and alkaline phosphatase levels. The absence of systemic symptoms, namely weight loss in excess of 10%, fever or night sweats, had less prognostic implication. Sex and stage (III or IV) did not significantly affect survival.
对95例晚期非霍奇金淋巴瘤（NHL）患者进行研究，以评估影响其生存的参数。中位生存时间为52个月（范围3 - 107个月）。采用对数秩检验分析数据。显著影响精算生存的有利参数为结节性组织学（P = 0.01）、年龄小于50岁（P = 0.002）、良好的体能状态（P = 0.006）以及血清乳酸脱氢酶、谷草转氨酶和碱性磷酸酶水平正常。无全身症状，即体重减轻超过10%、发热或盗汗，对预后的影响较小。性别和分期（III期或IV期）对生存无显著影响。
