Department of Physical Therapy, University of Illinois at Chicago, Chicago, Illinois, United States.
Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois, United States.
J Musculoskelet Neuronal Interact. 2024 Dec 1;24(4):353-360.
To investigate the effect of ischemic preconditioning (IC) on bilateral hip abductor strength, fatigue, and power in patients with knee osteoarthritis (KOA).
Participants (n=10) with KOA completed isokinetic and isometric hip abductor assessments on a Biodex dynamometer both before and after IC. IC was administered during a single session and consisted of 5 minutes of inflation (225mmHg) followed by 5 minutes of reperfusion for 50 minutes. Changes in strength and endurance measures before and after IC were compared using paired t-tests and magnitude of significant differences were reported using Cohen's d effect sizes.
Isokinetic hip abductor peak torque (d=.42, p=.027) and average power (d=.57, p=.029) in the involved limb, and isokinetic peak torque (d=.37, p=.044) in the uninvolved limb increased significantly after IC compared to baseline. There were no changes in isokinetic average power in the uninvolved limb, or isometric peak torque and fatigue index in both limbs after IC (p=.13-.77).
A single session of IC improved hip abductor strength in both limbs and power in the involved limb in KOA patients. IC should continue to be investigated as a safe and clinically convenient intervention that can supplement traditional modalities to improve muscle function in KOA.
探讨缺血预处理（IC）对膝骨关节炎（KOA）患者双侧髋外展肌力量、疲劳和功率的影响。
10 名 KOA 患者在接受 IC 前后均在 Biodex 测力计上进行等速和等长髋外展评估。IC 在单次治疗中进行，包括 5 分钟充气（225mmHg），随后再灌注 5 分钟，共 50 分钟。使用配对 t 检验比较 IC 前后力量和耐力测量值的变化，并使用 Cohen's d 效应大小报告显著差异的幅度。
与基线相比，IC 后受累侧的等速髋外展峰值扭矩（d=.42，p=.027）和平均功率（d=.57，p=.029），以及非受累侧的等速峰值扭矩（d=.37，p=.044）均显著增加。IC 后非受累侧的等速平均功率，或双侧的等长峰值扭矩和疲劳指数均无变化（p=.13-.77）。
单次 IC 可改善 KOA 患者双侧髋外展肌的力量和受累侧的功率。IC 应继续作为一种安全且临床方便的干预措施进行研究，以补充传统治疗方式，改善 KOA 患者的肌肉功能。
