Vioapeikonisi OE Imaging Lab, Heraklion Crete, Greece.
Radiology Department, General Hospital of Athens "G. Gennimatas", Athens, Greece.
J Musculoskelet Neuronal Interact. 2024 Dec 1;24(4):377-384.
To assess the performance of five osteoporosis clinical risk assessment tools (SCORE, ORAI, ABONE, OST and OSIRIS), in a subgroup of young postmenopausal women aged 50-64, who underwent DXA screening.
The above-mentioned osteoporosis risk assessment tools were calculated for 258 young postmenopausal women (aged 50-64) who had a DXA scan, in Crete/Greece.
Patients with a T-score ≤ -2.5 or a T-score ≤ -2.0 had a statistically significant higher value of SCORE, ORAI and ABONE and a lower value of OST, OSIRIS, and OSIRIS Adjusted Score, compared to the patients with T-score > -2.5 and T-score > -2.0, respectively. ORAI (T-score≤ -2.0) and OST (T-score≤ -2.5) demonstrated the highest sum of sensitivity and specificity. CHAID analysis further confirmed the relative significance of the OST tool in the osteoporosis group (T-score≤ -2.5 vs. T-score > -2.5), for a cut-off of 2.8. In the other group (T-score ≤ -2.0 vs T-score > -2.0) the ORAI score showed a significantly important relationship for a cut-off of 8.
OST, despite its performance limitations, correlates best with the DXA measurements of young (50-64), postmenopausal osteoporotic women, a fact which may suggest its' potential role as a screening tool in this specific age group.
评估 5 种骨质疏松临床风险评估工具（SCORE、ORAI、ABONE、OST 和 OSIRIS）在接受 DXA 筛查的 50-64 岁年轻绝经后女性亚组中的性能。
为在克里特岛/希腊接受 DXA 扫描的 258 名年轻绝经后（50-64 岁）女性计算了上述骨质疏松风险评估工具。
与 T 评分> -2.5 和 T 评分> -2.0 的患者相比，T 评分≤-2.5 或 T 评分≤-2.0 的患者的 SCORE、ORAI 和 ABONE 值具有统计学意义更高，而 OST、OSIRIS 和 OSIRIS 调整评分则更低。ORAI（T 评分≤-2.0）和 OST（T 评分≤-2.5）表现出最高的敏感性和特异性总和。CHAID 分析进一步证实了 OST 工具在骨质疏松组（T 评分≤-2.5 与 T 评分>-2.5）中的相对重要性，截断值为 2.8。在另一组（T 评分≤-2.0 与 T 评分>-2.0）中，ORAI 评分与 T 评分>-2.0 相比具有显著的重要关系，截断值为 8。
OST 尽管性能有限，但与年轻（50-64 岁）绝经后骨质疏松女性的 DXA 测量结果相关性最佳，这一事实可能表明其在特定年龄组中作为筛查工具的潜在作用。
