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本文引用的文献

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Delirium detection in the emergency department: A diagnostic accuracy meta-analysis of history, physical examination, laboratory tests, and screening instruments.急诊科谵妄检测:病史、体格检查、实验室检查和筛查工具的诊断准确性荟萃分析。
Acad Emerg Med. 2024 Oct;31(10):1014-1036. doi: 10.1111/acem.14935. Epub 2024 May 16.
2
Diagnostic accuracy of Ascertain Dementia 8-item Questionnaire by participant and informant-A systematic review and meta-analysis.参与者和知情人评估的 Ascertain Dementia 8 项问卷的诊断准确性:系统评价和荟萃分析。
PLoS One. 2023 Sep 12;18(9):e0291291. doi: 10.1371/journal.pone.0291291. eCollection 2023.
3
Emergency department care transition barriers: A qualitative study of care partners of older adults with cognitive impairment.急诊科护理过渡障碍:对认知障碍老年人护理伙伴的定性研究。
Alzheimers Dement (N Y). 2022 Sep 28;8(1):e12355. doi: 10.1002/trc2.12355. eCollection 2022.
4
Optimal Emergency Department Care Practices for Persons Living With Dementia: A Scoping Review.优化痴呆患者的急诊护理实践:范围综述。
J Am Med Dir Assoc. 2022 Aug;23(8):1314.e1-1314.e29. doi: 10.1016/j.jamda.2022.05.024.
5
Detecting Cognitive Impairment and Dementia in the Emergency Department: A Scoping Review.急诊科认知障碍和痴呆的检测:范围综述。
J Am Med Dir Assoc. 2022 Aug;23(8):1314.e31-1314.e88. doi: 10.1016/j.jamda.2022.03.019.
6
A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research.可靠性研究中组内相关系数选择与报告指南
J Chiropr Med. 2016 Jun;15(2):155-63. doi: 10.1016/j.jcm.2016.02.012. Epub 2016 Mar 31.
7
Anosognosia in people with cognitive impairment: association with cognitive deficits and behavioral disturbances.认知障碍患者的疾病感缺失:与认知缺陷及行为障碍的关联
Dement Geriatr Cogn Dis Extra. 2015 Feb 17;5(1):42-50. doi: 10.1159/000367987. eCollection 2015 Jan-Apr.
8
Subjective cognitive decline: self and informant comparisons.主观认知衰退:自我与知情人比较。
Alzheimers Dement. 2014 Jan;10(1):93-8. doi: 10.1016/j.jalz.2013.01.003. Epub 2013 Apr 3.
9
Cognitive Impairment among Older Adults in the Emergency Department.急诊科老年患者的认知障碍。
West J Emerg Med. 2011 Feb;12(1):56-62.
10
Four sensitive screening tools to detect cognitive dysfunction in geriatric emergency department patients: brief Alzheimer's Screen, Short Blessed Test, Ottawa 3DY, and the caregiver-completed AD8.四种用于检测老年急诊科患者认知功能障碍的敏感筛查工具:简要阿尔茨海默病筛查、简短Blessed 测试、渥太华 3DY 和照顾者完成的 AD8。
Acad Emerg Med. 2011 Apr;18(4):374-84. doi: 10.1111/j.1553-2712.2011.01040.x.

急诊科认知障碍筛查:老年患者及 informant 完成的 Ascertain Dementia 8 工具之间的一致性

Screening for Cognitive Impairment in the Emergency Department: Agreement between Older Adult Patient- and Informant-Completed Ascertain Dementia 8 Tool.

作者信息

Galske James, Sather Anna, Chera Tonya, Hwang Ula, Carpenter Christopher R, Babcock Matthew, Gettel Cameron J

机构信息

Department of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA.

Icahn School of Medicine at Mount Sinai, New York, New York, USA.

出版信息

Dement Geriatr Cogn Disord. 2025;54(3):160-166. doi: 10.1159/000542895. Epub 2024 Nov 29.

DOI:10.1159/000542895
PMID:39616991
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12119964/
Abstract

INTRODUCTION

Emergency department (ED) screening for cognitive impairment (CI) is crucial for early intervention, yet guidance on dementia screening protocols remains limited. Our objective was to assess the concordance between the Ascertain Dementia 8 (AD8) tool, a brief screening tool for CI, administered to ED patients and their informants.

METHODS

We conducted a prospective observational study of dyads, including patients ≥65 years without a diagnosis of dementia seeking care in the ED and their informants (e.g., family, friend with close contact). Trained research assistants used the 4AT to exclude patients with concern for delirium. The AD8 was then administered to blinded patients (pAD8) and informants (iAD8), with scores ranging from 0 to 8 and scores of ≥2 indicating CI. We used the intraclass correlation coefficient (ICC) to calculate the level of agreement between AD8 scores.

RESULTS

Our analytic sample included 538 dyads, of which 63.3% of patients were female with a mean age of 73.5 years. A total of 131 (24.3%) patients without a diagnosis of dementia self-identified as having CI using the pAD8, in comparison to 110 (20.4%) informants using the iAD8. The ICC of 0.519 (95% CI 0.454-0.578) indicated moderate agreement between pAD8 and iAD8 scores.

CONCLUSIONS

When seeking emergency care, one in four older adults without a diagnosis of dementia and approximately 20% of informants indicated that patients were cognitively impaired. Our finding of moderate agreement between the pAD8 and iAD8 has important implications for clinicians providing care to patients with suspected CI and investigators conducting dementia-related studies.

摘要

引言

急诊科(ED)对认知障碍(CI)进行筛查对于早期干预至关重要,但关于痴呆筛查方案的指导仍然有限。我们的目的是评估用于急诊科患者及其 informant 的认知障碍简短筛查工具——确定痴呆 8 项(AD8)工具之间的一致性。

方法

我们对成对个体进行了一项前瞻性观察性研究,包括在急诊科就诊且未被诊断为痴呆的≥65 岁患者及其 informant(如家人、密切接触的朋友)。经过培训的研究助理使用 4AT 排除有谵妄疑虑的患者。然后对不知情的患者(pAD8)和 informant(iAD8)进行 AD8 评估,分数范围为 0 至 8,≥2 分表示存在认知障碍。我们使用组内相关系数(ICC)来计算 AD8 分数之间的一致程度。

结果

我们的分析样本包括 538 对,其中 63.3%的患者为女性,平均年龄为 73.5 岁。共有 131 名(24.3%)未被诊断为痴呆的患者使用 pAD8 自我认定存在认知障碍,相比之下,110 名(20.4%) informant 使用 iAD8 得出相同结论。ICC 为 0.519(95%可信区间 0.454 - 0.578)表明 pAD8 和 iAD8 分数之间存在中度一致性。

结论

在寻求急诊护理时,四分之一未被诊断为痴呆的老年人以及约 20%的 informant 表示患者存在认知障碍。我们发现 pAD8 和 iAD8 之间存在中度一致性,这对于为疑似认知障碍患者提供护理的临床医生以及进行痴呆相关研究的研究人员具有重要意义。