Chen Yi-Chen, Wang Hsuan-Yun, Ogita Futoshi, Hung Chi-Hsiang, Kuo Chia-Hua, Wang Jie-Ping, Wang Chia-Min, Hou Chien-Wen, Wang Ting-Yao
University of Taipei, Laboratory of Exercise Biochemistry, Institute of Sports Sciences, Taipei, Taiwan.
National Institute of Fitness and Sports in Kanoya, Department of Sports and Life Sciences, Kanoya, Japan.
J Int Soc Sports Nutr. 2024 Dec;21(1):2425609. doi: 10.1080/15502783.2024.2425609. Epub 2024 Dec 1.
High-intensity interval training (HIIT) has been shown to improve chronic diseases. Probiotics have been found to have similar effects. However, the additive effects of HIIT in combination with probiotics supplementation are unclear. The aim of current study was to investigate whether there were additive effects when implementing both HIIT and probiotics simultaneously.
Forty-seven obese middle-aged women (Age: 44.5 ± 5.94 years, body fat percentage: 40.0 ± 4.1%) were recruited and assigned into four groups: control group (C, = 12), probiotics group (P, = 12), HIIT group (H, = 11), and HIIT with probiotics group (HP, = 12). All the participants consumed probiotics TWK10, 6 × 10 CFU/day) or placebo supplements daily. Exercise intervention groups conducted HIIT training (85-90% vVOmax for 2 min, followed by a 1-min inactive rest interval, repeated for 7 cycles) 3 sessions per week for 8 weeks. Anthropometry, cardiorespiratory endurance, blood glucose, and lipid profile were measured at baseline and after the 8-week intervention.
After the intervention, there were significant changes between groups in the variations and rates of change in waist circumference, hip circumference, and TTE. The waist circumference in group H significantly increased compared to groups C and P, while group HP did not show significant difference compared to group C. On the other hand, the hip circumference decreased significantly in group HP compared to group C, and the decreased rate in group HP was significantly greater than in groups C and P. Furthermore, the increase rates in TTE were higher in group H and HP compared to group C.
HIIT improves TTE but negatively affects waist circumference compared to the control group. However, when combined with probiotics, the probiotics not only help enhance TTE but also counteract the negative impact on waist circumference and further reduce hip circumference, resulting in a synergistic effect.
ClinicalTrials.gov, identifier NCT06285578.
高强度间歇训练（HIIT）已被证明可改善慢性疾病。益生菌也被发现有类似效果。然而，HIIT与补充益生菌的叠加效应尚不清楚。本研究的目的是调查同时进行HIIT和补充益生菌时是否存在叠加效应。
招募47名肥胖中年女性（年龄：44.5±5.94岁，体脂百分比：40.0±4.1%），并将其分为四组：对照组（C，n = 12）、益生菌组（P，n = 12）、HIIT组（H，n = 11）和HIIT加益生菌组（HP，n = 12）。所有参与者每天服用益生菌TWK10（6×10⁸CFU/天）或安慰剂补充剂。运动干预组每周进行3次HIIT训练（以85 - 90%的峰值摄氧量进行2分钟，随后进行1分钟的非活动休息间隔，重复7个循环），共8周。在基线和8周干预后测量人体测量学指标、心肺耐力、血糖和血脂谱。
干预后，各组腰围、臀围和总运动时间（TTE）的变化量和变化率存在显著差异。与C组和P组相比，H组的腰围显著增加，而HP组与C组相比无显著差异。另一方面，与C组相比，HP组的臀围显著减小，且HP组的减小率显著大于C组和P组。此外，与C组相比，H组和HP组的TTE增加率更高。
与对照组相比，HIIT可改善TTE，但对腰围有负面影响。然而，与益生菌联合使用时，益生菌不仅有助于提高TTE，还能抵消对腰围的负面影响，并进一步减小臀围，产生协同效应。
ClinicalTrials.gov，标识符NCT06285578。
