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小儿成熟畸胎瘤的非典型表现:一例病例报告及文献复习

An Atypical Presentation of a Pediatric Mature Teratoma: A Case Report and Review of the Literature.

作者信息

Othman Ahmed M, Abu Alnasr Abdulaziz A, Kordi Reem E, Abu Alnasr Shahad A

机构信息

Emergency Department, Prince Mohammed Bin Abdulaziz Hospital, Madinah, SAU.

Family Medicine Department, Prince Mohammed Bin Abdulaziz National Guard Hospital, Madinah, SAU.

出版信息

Cureus. 2024 Oct 31;16(10):e72746. doi: 10.7759/cureus.72746. eCollection 2024 Oct.

DOI:10.7759/cureus.72746
PMID:39618635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11607561/
Abstract

Immature teratoma is an uncommon type of malignant tumor that mostly consists of immature tissue originating from the neuroepithelium. Mature teratomas in pediatrics are relatively rare and difficult to diagnose because of various symptoms and the tendency to overlap with other illnesses. This study aimed to report a rare case of a mature teratoma in pediatric age. A Saudi female patient, aged 31 months, was brought to the emergency room (ER) in 2024 with a suprapubic mass. She did not complain of pain or urinary symptoms and had no substantial medical or family history, and the mass was discovered incidentally. A non-tender suprapubic mass was found during a physical examination. A large cystic mass containing fat and calcification was seen during imaging tests (pelvic CT and MRI), and this diagnosis was consistent with the presence of an ovarian dermoid cyst. The surgical intervention involved laparotomy with right oophorectomy, and the tumor was identified by pathological investigation as a mature teratoma, distinguished by a cystic structure packed with hair, gelatinous material, and bone components. Following the surgery, there were no issues, and a follow-up appointment was scheduled to monitor any complications. This case emphasizes the rarity and difficulties in diagnosing mature teratomas in pediatric patients, with positive and promising outcomes highlighting that a comprehensive diagnostic approach and a customized treatment plan are essential for a smooth recovery from ovarian lesions in pediatrics. Consequently, accurate diagnosis and quick surgical intervention are critical for optimal management, even in the absence of obvious symptoms.

摘要

未成熟畸胎瘤是一种罕见的恶性肿瘤,主要由起源于神经上皮的未成熟组织构成。儿科中的成熟畸胎瘤相对少见,由于症状多样且易与其他疾病重叠,故难以诊断。本研究旨在报告一例儿科年龄的成熟畸胎瘤罕见病例。一名31个月大的沙特女性患者于2024年因耻骨上肿块被送往急诊室。她没有疼痛或泌尿系统症状的主诉,也没有重大的病史或家族史,肿块是偶然发现的。体格检查时发现一个无压痛的耻骨上肿块。影像学检查(盆腔CT和MRI)显示一个含有脂肪和钙化的大囊性肿块,该诊断与卵巢皮样囊肿相符。手术干预包括剖腹手术及右侧卵巢切除术,病理检查确定肿瘤为成熟畸胎瘤,其特征为充满毛发、胶冻样物质和骨成分的囊性结构。手术后未出现问题,并安排了随访预约以监测任何并发症。该病例强调了儿科患者中成熟畸胎瘤诊断的罕见性和困难,积极且良好的结果表明,全面的诊断方法和定制的治疗方案对于儿科卵巢病变的顺利康复至关重要。因此,即使没有明显症状,准确诊断和快速手术干预对于最佳治疗管理也至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d4/11607561/13bd7370aaf0/cureus-0016-00000072746-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d4/11607561/3429a68f8274/cureus-0016-00000072746-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d4/11607561/ab284a9bc22b/cureus-0016-00000072746-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d4/11607561/13bd7370aaf0/cureus-0016-00000072746-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d4/11607561/3429a68f8274/cureus-0016-00000072746-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d4/11607561/ab284a9bc22b/cureus-0016-00000072746-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d4/11607561/13bd7370aaf0/cureus-0016-00000072746-i03.jpg

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Mature Cystic Teratoma: An Integrated Review.成熟囊性畸胎瘤:综合评价。
Int J Mol Sci. 2023 Mar 24;24(7):6141. doi: 10.3390/ijms24076141.
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Ovarian Teratomas in Children and Adolescents: Our Own Experience and Review of Literature.儿童及青少年卵巢畸胎瘤:我们的经验及文献综述
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