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儿童及青少年卵巢畸胎瘤:我们的经验及文献综述

Ovarian Teratomas in Children and Adolescents: Our Own Experience and Review of Literature.

作者信息

Gkrozou Fani, Tsonis Orestis, Vatopoulou Anastasia, Galaziou Georgia, Paschopoulos Minas

机构信息

Department of Obstetrics and Gynaecology, Medical School, University of Ioannina, 45500 Ioannina, Greece.

Assisted Conception Unit, Guy's and St Thomas' NHS Foundation Trust, London SE1 9RT, UK.

出版信息

Children (Basel). 2022 Oct 18;9(10):1571. doi: 10.3390/children9101571.

DOI:10.3390/children9101571
PMID:36291507
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9599961/
Abstract

: Ovarian teratomas are the most common type of ovarian mass during childhood and adolescence. There is no clear guidance for the management of the ovarian teratomas in children and adolescents. It is necessary, however, to understand the feature of these tumours and the indications for operating on them, and to put subjective criteria for the management in elective or emergency presentations. : Medical records of patients between the age of 12 and 20 years old that underwent surgery for ovarian teratomas at the Department of Obstetrics and Gynaecology in University Hospital of Ioannina, between January 2000 and August 2022, were reviewed. A medical database was searched between January 2000 and August 2022 with the following keywords: ovarian teratoma, paediatrics and adolescents. : We present the results of forty patients, with a mean age of 11.8 years of age. All patients had surgery, where three out of four underwent oophorectomy and only one out of four underwent ovary-sparing operation; similar results were found in the literature. : Ovary-sparing treatment is more common recently compared with the past, such as MIS compared with laparotomy. Better-organised and -planned prospective multi-centre studies are necessary to gain a deeper knowledge of the physiology and prognostic factors of teratomas in children.

摘要

卵巢畸胎瘤是儿童和青少年时期最常见的卵巢肿物类型。对于儿童和青少年卵巢畸胎瘤的管理,目前尚无明确的指导意见。然而,有必要了解这些肿瘤的特征以及对其进行手术的指征,并针对择期或急诊情况下的管理制定主观标准。

回顾了2000年1月至2022年8月期间在约阿尼纳大学医院妇产科接受卵巢畸胎瘤手术的12至20岁患者的病历。在2000年1月至2022年8月期间,使用以下关键词对医学数据库进行了检索:卵巢畸胎瘤、儿科和青少年。

我们展示了40例患者的结果,平均年龄为11.8岁。所有患者均接受了手术,其中四分之三接受了卵巢切除术,只有四分之一接受了保留卵巢的手术;文献中也发现了类似的结果。

与过去相比,保留卵巢的治疗最近更为常见,例如与开腹手术相比,微创治疗更为常见。有必要开展组织更完善、计划更周密的前瞻性多中心研究,以更深入地了解儿童畸胎瘤的生理学和预后因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b26d/9599961/f2e96cff7cad/children-09-01571-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b26d/9599961/f2e96cff7cad/children-09-01571-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b26d/9599961/f2e96cff7cad/children-09-01571-g001.jpg

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Ovarian teratoma in a teenager causing ureterohydronephrosis: Case report and literature review.青少年卵巢畸胎瘤致输尿管积水:病例报告及文献复习。
Medicine (Baltimore). 2021 Jul 9;100(27):e26472. doi: 10.1097/MD.0000000000026472.
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Management of pediatric benign ovarian tumors in England and Egypt: A comparative study.
Front Oncol. 2025 Jun 17;15:1565865. doi: 10.3389/fonc.2025.1565865. eCollection 2025.
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Renal immature teratoma in infant: A rare case report.婴儿肾未成熟畸胎瘤:一例罕见病例报告。
Urol Case Rep. 2025 Jan 30;59:102967. doi: 10.1016/j.eucr.2025.102967. eCollection 2025 Mar.
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An Atypical Presentation of a Pediatric Mature Teratoma: A Case Report and Review of the Literature.小儿成熟畸胎瘤的非典型表现:一例病例报告及文献复习
Cureus. 2024 Oct 31;16(10):e72746. doi: 10.7759/cureus.72746. eCollection 2024 Oct.
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