Frizzell L A, Miller D L, Nyborg W L
Ultrasound Med Biol. 1986 Mar;12(3):217-21. doi: 10.1016/0301-5629(86)90312-1.
Ultrasonically induced microstreaming around bubbles of gas have been shown to cause damage to biological materials in vitro at clinical exposure levels. The potential for ultrasonically induced cavitation and microstreaming in mammalian systems is of interest with respect to the safe application of clinical ultrasound. Ultrasonically induced intravascular microstreaming and formation of thrombi at 1 MHz is demonstrated adjacent the tip of a micropipette in contact with a mesenteric vessel of the mouse. These effects occur at or above therapeutic levels.
已经表明，在临床暴露水平下，超声诱导的围绕气泡的微流会在体外对生物材料造成损伤。就临床超声的安全应用而言，哺乳动物系统中超声诱导的空化和微流的可能性备受关注。在与小鼠肠系膜血管接触的微量移液器尖端附近，证实了在1兆赫兹时超声诱导的血管内微流和血栓形成。这些效应在治疗水平或高于治疗水平时出现。
