肩袖修复中的生物学策略：临床应用与分子背景

Pawlak Maciej, Wałecka Joanna, Lubiatowski Przemysław

Rehasport Clinic, Poznań-Gdańsk, Poland.

Sport Traumatology and Biomechanics Unit, Department of Traumatology, Orthopaedics and Hand Surgery, Poznań University of Medical Science, Poznań, Poland.

EFORT Open Rev. 2024 Dec 2;9(12):1156-1169. doi: 10.1530/EOR-24-0012.

Conventional repair of rotator cuff tears bears a variable but significant risk of incomplete healing. Biological therapies that accompany surgical rotator cuff repair include platelet-rich plasma, stem cells of different origins, and biological scaffolds. Biological therapies facilitate the regeneration of the correct microarchitecture of the tendon attachment to the bone and reduce failures after surgical rotator cuff repair.

传统的肩袖撕裂修复术存在愈合不完全的风险，其风险程度不一但较为显著。伴随手术性肩袖修复的生物疗法包括富血小板血浆、不同来源的干细胞以及生物支架。生物疗法有助于肌腱与骨骼附着处正确微观结构的再生，并减少手术性肩袖修复后的失败情况。