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用于在胃肠道内安全高效移动的哑铃形气球锚定致动器的设计与分析建模

Design and Analytical Modeling of a Dumbbell-Shaped Balloon Anchoring Actuator for Safe and Efficient Locomotion Inside Gastrointestinal Tract.

作者信息

Ren Xuyang, Pan Tianle, Dario Paolo, Wang Shuxin, Chiu Philip Wai Yan, Ciuti Gastone, Li Zheng

机构信息

Multiscale Medical Robotics Centre Ltd., The Chinese University of Hong Kong, Shatin, Hong Kong.

Chow Yuk Ho Technology Centre for Innovative Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

出版信息

Soft Robot. 2025 Jun;12(3):374-385. doi: 10.1089/soro.2024.0037. Epub 2024 Dec 2.

Abstract

Colorectal cancer stands as one of the most prevalent cancers globally, representing 9.8% of total cases and contributing to 9.2% of mortalities annually. Robotic "front-wheel" navigating colonoscopes mitigate aggressive stretching against the long and tortuous colonic wall, alleviating associated discomfort and pain typically experienced by patients inspected by conventional "back-wheel" navigating colonoscopes. The anchoring unit of most "front-wheel" navigating colonoscopes plays a crucial role in ensuring effective locomotion by preventing slipping during elongation/contraction of the central actuation part. The soft balloon anchoring actuator emerges as a promising solution due to its high compliance. This study introduces a dumbbell-shaped balloon anchoring actuator (DBAA) integrating an "inflation and suction" mechanism to address the inherent conflict between achieving sufficient anchoring force and minimizing expansion and potential trauma of the colonic wall, commonly encountered in current balloon anchoring actuators. Analytical modeling of DBAA and soft external lumen, encompassing geometric deformation and anchoring force, were proposed to characterize the actuator and provide guidelines for designing and controlling DBAA in further applications, enabling autonomous anchoring within different diameter lumens and achieving the expected anchoring force. A comprehensive set of validation experiments was conducted, and the outcomes revealed high consistency with analytical predictions, confirming the effectiveness of the proposed analytical modeling approach. Furthermore, the results demonstrated a significant enhancement in anchoring force with the proposed actuator and corresponding mechanism while concurrently maintaining low-lumen expansion. For instance, in a lumen sample with the anchoring force reaches 14.5 N with 50 kPa negative pressure, which is 12.4 times of the force (1.17 N) observed without applying negative pressure.

摘要

结直肠癌是全球最常见的癌症之一,占总病例数的9.8%,每年导致9.2%的死亡率。机器人“前轮”导航结肠镜可减轻对长而曲折的结肠壁的强力拉伸,减轻患者在接受传统“后轮”导航结肠镜检查时通常会经历的相关不适和疼痛。大多数“前轮”导航结肠镜的锚定单元在确保有效移动方面起着关键作用,通过防止中央驱动部分伸长/收缩时滑动。软球囊锚定致动器因其高顺应性而成为一种有前景的解决方案。本研究介绍了一种集成“充气和抽吸”机制的哑铃形球囊锚定致动器(DBAA),以解决当前球囊锚定致动器中常见的在实现足够的锚定力与最小化结肠壁扩张和潜在创伤之间的内在冲突。提出了DBAA和软外腔的分析模型,包括几何变形和锚定力,以表征该致动器,并为进一步应用中DBAA的设计和控制提供指导,使其能够在不同直径的腔内自主锚定并实现预期的锚定力。进行了一套全面的验证实验,结果显示与分析预测高度一致,证实了所提出的分析建模方法的有效性。此外,结果表明,所提出的致动器和相应机制显著提高了锚定力,同时保持了低腔扩张。例如,在一个腔样本中,在50 kPa负压下,锚定力达到14.5 N,是未施加负压时观察到的力(1.17 N)的12.4倍。

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