Munroe Sarah, Schackman Bruce R, Madkins Krystal, Saber Rana, Macapagal Kathryn, Vititow Jocelyn, Sweeney Nicholas, Feder Noah M, Benbow Nanette, Mustanski Brian, Linas Benjamin P
Department of Medicine, Section of Infectious Diseases, Boston Medical Center, Boston, MA.
Department of Population Health Sciences, Weill Cornell Medicine, New York, NY.
J Acquir Immune Defic Syndr. 2025 Mar 1;98(3):257-264. doi: 10.1097/QAI.0000000000003572.
This study, conducted as part of the Keep It Up! (KIU!) 3.0 trial, compares the implementation costs of 2 strategies-centralized direct-to-consumer (DTC) marketing and decentralized distribution through community-based organizations (CBO)-in delivering an evidence-based online HIV prevention program.
We conducted interviews and collected data to identify and quantify all costs for both delivery strategies. Costs were then categorized into start-up and ongoing (time-dependent and variable) costs and assigned dollar values based on established microcosting protocols.
In the DTC arm (1468 enrollees), the program was implemented from October 2019 through August 2022. Total ongoing costs including overhead and excluding start-up costs were $735,953, averaging $501 per participant. Start-up costs were $398,384 ($376,393 for content design and development and $21,991 for other costs), time-dependent costs were $219,177 ($149 per participant), and variable costs were $491,658 ($335 per participant). In the CBO arm (656 enrollees across 22 sites), KIU! was implemented for a 2-year period between October 2019 and December 2022. Total ongoing costs including overhead and excluding start-up costs were $2,780,682 ($4239 per participant). Start-up costs were $511,528 ($401,141 for content design and development and $110,386 for other costs), time-dependent costs were $1,926,958 ($2937 per participant), and variable costs were $256,543 ($391 per participant).
The DTC arm demonstrated a lower overall cost and a lower cost per participant than distribution by the CBO arm. Understanding these cost dynamics is pivotal for guiding decisions on program sustainability and determining funding requirements for future large-scale implementation.
本研究作为“坚持下去!”(KIU!)3.0试验的一部分,比较了两种策略——集中式直接面向消费者(DTC)营销和通过社区组织(CBO)进行分散式分发——在提供基于证据的在线艾滋病毒预防项目时的实施成本。
我们进行了访谈并收集数据,以识别和量化两种交付策略的所有成本。然后将成本分为启动成本和持续(时间相关和可变)成本,并根据既定的微观成本核算方案赋予美元价值。
在DTC组(1468名参与者)中,该项目于2019年10月至2022年8月实施。包括间接费用且不包括启动成本的总持续成本为735,953美元,平均每位参与者501美元。启动成本为398,384美元(内容设计和开发为376,393美元,其他成本为21,991美元),时间相关成本为219,177美元(每位参与者149美元),可变成本为491,658美元(每位参与者335美元)。在CBO组(22个地点的656名参与者)中,KIU!在2019年10月至2022年12月期间实施了两年。包括间接费用且不包括启动成本的总持续成本为2,780,682美元(每位参与者4239美元)。启动成本为511,528美元(内容设计和开发为401,141美元,其他成本为110,386美元),时间相关成本为1,926,958美元(每位参与者2937美元),可变成本为256,543美元(每位参与者391美元)。
DTC组的总体成本和每位参与者的成本均低于CBO组的分发成本。了解这些成本动态对于指导项目可持续性决策和确定未来大规模实施的资金需求至关重要。