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[痣和恶性黑色素瘤游离基质细胞的形态计量分析]

[Morphometric analysis of the free stromal cells of nevi and malignant melanomas].

作者信息

Nikitin A Iu

出版信息

Vopr Onkol. 1986;32(2):15-9.

PMID:3962239
Abstract

A morphologic study of 114 cases of pigmented skin tumors was carried out. The cases were divided into 5 groups on the basis of the degree of nevus proliferation and depth of melanoma invasion. The percentage and correlation between different types of free stromal cells were obtained for different skin zones in 6 cases of each group. Correlation analysis established the set character of cell cooperation at different stages of tumor growth. Diagrams illustrating correlations between free stromal cells and pigmented formations patterns are discussed. The results of the study may be helpful in running diagnostic tests of nevi for malignancy as well as identifying the depth of melanoma invasion whenever visual morphologic examination is insufficient.

摘要

对114例色素性皮肤肿瘤进行了形态学研究。根据痣细胞增生程度和黑色素瘤浸润深度将病例分为5组。每组选取6例,获取不同皮肤区域不同类型游离基质细胞的百分比及相关性。相关性分析确定了肿瘤生长不同阶段细胞协作的集合特征。讨论了说明游离基质细胞与色素沉着形成模式之间相关性的图表。该研究结果可能有助于进行痣的恶性诊断测试,以及在视觉形态学检查不足时确定黑色素瘤的浸润深度。

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