Steigleder G K, Uerdingen R
Hautarzt. 1976 Apr;27(4):153-4.
Using microradiograms (x-rays of histological sections) and polarized light, we examined collagenous tissue surrounding junctional nevi, benign juvenile melanomas, Dubreuilh's melanosis and early malignant melanomas similar to junctional nevi. Wherever there were tumor cells and infiltrates the collagenous tissue was reduced or destroyed, but had not usually been pushed aside as claimed in previous accounts. The absence of a connective tissue membrane, comparable to the border-zone beneath the epidermis, argues against a nevus. Mature collagenous bundles are clearly shown up by microradiograms and by pollarized light. The degree of thier destruction does not make it possible to distinguish between nevi and malignant melanomas.
我们使用微射线照片（组织学切片的X射线）和偏振光，检查了交界痣、良性幼年黑素瘤、杜布雷伊黑素沉着症以及与交界痣相似的早期恶性黑素瘤周围的胶原组织。只要有肿瘤细胞和浸润，胶原组织就会减少或被破坏，但通常并没有像之前报道中所说的那样被推开。没有与表皮下边界区类似的结缔组织膜，这与痣的情况不符。微射线照片和偏振光清楚地显示出成熟的胶原束。它们的破坏程度无法区分痣和恶性黑素瘤。
