Suppr超能文献

一项横断面研究,评估莫桑比克 - 加拿大孕产妇健康项目提取工具在莫桑比克伊尼扬巴内省识别孕产妇接近死亡情况方面的有效性。

Cross-sectional study evaluating the effectiveness of the Mozambique-Canada maternal health project abstraction tool for maternal near miss identification in Inhambane province, Mozambique.

作者信息

Muosieyiri Maud, Forsyth Jessie, Andre Fernanda, Ferrão da Silva Adoni Ana Paula, Muhajarine Nazeem

机构信息

Biostatistics and Epidemiology, University of Massachusetts Amherst, Amherst, Massachusetts, USA

Community Health and Epidemiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

出版信息

BMJ Open. 2024 Dec 2;14(12):e091517. doi: 10.1136/bmjopen-2024-091517.

Abstract

OBJECTIVES

The objectives of this study are to determine whether the additional clinical criteria of the Mozambique maternal near miss abstraction tool enhance the effectiveness of the original WHO abstraction tool in identifying maternal near miss cases and also evaluate the impact of sociodemographic factors on maternal near miss identification.

DESIGN

Cross-sectional study.

SETTING

Two secondary referral hospitals in Inhambane province, Mozambique from 2021 to 2022.

PARTICIPANTS

From August 2021 to February 2022, 2057 women presenting at two hospitals in Inhambane Province, Mozambique, were consecutively enrolled. Eligible participants included women admitted during pregnancy, labour, delivery, or up to 42 days post partum. Selection criteria focused on women experiencing obstetric complications, while those without complications or with incomplete medical records were excluded.

PRIMARY AND SECONDARY OUTCOME MEASURES

The primary outcome was identifying maternal near miss cases using the original WHO Disease criterion and the additional clinical criteria from the Mozambique-Canada Maternal Health Project abstraction tool. Secondary outcomes included the association between sociodemographic factors and maternal near miss identification. All outcomes were measured as planned in the study protocol.

RESULTS

The new Mozambique-Canada abstraction tool identified more maternal near miss cases (28.2% for expanded disease and 21.1% for comorbidities) compared with the original WHO tool (16.2%). Hypertension and anaemia from the newer criteria were strongly associated with the original WHO Disease criterion (p<0.001), with kappa values of 0.58 (95% CI 0.53 to 0.63) and 0.21 (95% CI 0.16 to 0.26), respectively. Distance to health facilities was significantly associated, with women living over 8 km away having higher odds (OR=2.47, 95% CI 1.92 to 3.18, p<0.001). Type of hospital also influenced identification, with lower odds at Vilankulo Rural Hospital for Expanded Disease criterion (OR=0.70, 95% CI 0.57 to 0.87, p=0.001), but higher odds for comorbidities criterion (OR=3.13, 95% CI 2.40 to 4.08, p<0.001). Finally, older age was associated with higher odds of identification under the comorbidities criterion, particularly for women aged 30-39 (OR=3.06, 95% CI 2.15 to 4.36) as well as those 40 years or older (OR=4.73, 95% CI 2.43 to 9.20, p<0.001).

CONCLUSIONS

The Mozambique-Canada Maternal Health Project tool enhances maternal near miss identification over the original WHO tool by incorporating expanded clinical criteria, particularly for conditions like hypertension and anaemia. Sociodemographic factors, including healthcare access, hospital type and maternal age, significantly impact near miss detection. These findings support integrating the expanded criteria into the WHO tool for improved identification of maternal near misses in Mozambique and similar low-resource settings. Future research should examine the tool's effectiveness across varied healthcare contexts and populations.

摘要

目的

本研究的目的是确定莫桑比克孕产妇险些死亡提取工具的附加临床标准是否能提高原始世界卫生组织(WHO)提取工具识别孕产妇险些死亡病例的有效性,并评估社会人口学因素对孕产妇险些死亡识别的影响。

设计

横断面研究。

地点

2021年至2022年期间,莫桑比克伊尼扬巴内省的两家二级转诊医院。

参与者

从2021年8月至2022年2月,连续招募了莫桑比克伊尼扬巴内省两家医院的2057名女性。符合条件的参与者包括在孕期、分娩期、产时或产后42天内入院的女性。选择标准侧重于有产科并发症的女性,而没有并发症或病历不完整的女性被排除在外。

主要和次要结局指标

主要结局是使用原始WHO疾病标准和莫桑比克-加拿大孕产妇健康项目提取工具的附加临床标准识别孕产妇险些死亡病例。次要结局包括社会人口学因素与孕产妇险些死亡识别之间的关联。所有结局均按照研究方案中的计划进行测量。

结果

与原始WHO工具(16.2%)相比,新的莫桑比克-加拿大提取工具识别出更多的孕产妇险些死亡病例(扩展疾病为28.2%,合并症为21.1%)。新标准中的高血压和贫血与原始WHO疾病标准密切相关(p<0.001),kappa值分别为0.58(95%CI 0.53至0.63)和0.21(95%CI 0.16至0.26)。与医疗机构的距离有显著关联,居住在8公里以上的女性识别出险些死亡病例的几率更高(OR=2.47,95%CI 1.92至3.18,p<0.001)。医院类型也影响识别,在维兰库洛农村医院,扩展疾病标准下识别出险些死亡病例的几率较低(OR=0.70,95%CI 0.57至0.87,p=0.001),但合并症标准下几率较高(OR=3.13,95%CI 2.40至4.08,p<0.001)。最后,年龄较大与合并症标准下识别出险些死亡病例的几率较高相关,特别是30至39岁的女性(OR=3.06,95%CI 2.15至4.36)以及40岁及以上的女性(OR=4.73,95%CI 2.43至9.20,p<0.001)。

结论

莫桑比克-加拿大孕产妇健康项目工具通过纳入扩展的临床标准,特别是高血压和贫血等病症的标准,比原始WHO工具更能提高孕产妇险些死亡的识别率。社会人口学因素,包括医疗服务可及性、医院类型和孕产妇年龄,对险些死亡的检测有显著影响。这些发现支持将扩展标准纳入WHO工具,以改善莫桑比克及类似资源匮乏地区孕产妇险些死亡的识别。未来的研究应考察该工具在不同医疗环境和人群中的有效性。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验