推出用于体内生物传感的全喷墨打印微针。

Introducing all-inkjet-printed microneedles for in-vivo biosensing.

作者信息

Rosati Giulio, Deroco Patricia Batista, Bonando Matheus Guitti, Dalkiranis Gustavo G, Cordero-Edwards Kumara, Maroli Gabriel, Kubota Lauro Tatsuo, Oliveira Osvaldo N, Saito Lúcia Akemi Miyazato, de Carvalho Castro Silva Cecilia, Merkoçi Arben

机构信息

Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, 08193, Bellaterra, Barcelona, Spain.

Institute of Chemistry, University of Campinas - UNICAMP, Campinas, 13083-970, Brazil.

出版信息

Sci Rep. 2024 Dec 2;14(1):29975. doi: 10.1038/s41598-024-80840-1.

DOI:10.1038/s41598-024-80840-1

PMID:39622853

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11612178/

Abstract

Microneedles are mainly used for pain-free drug administration and in biosensing for wearable systems. They are also promising for fields such as agronomy for precision farming, but their fabrication is not straightforward, often requiring expensive equipment and cleanroom protocols, being unsuitable for mass production. Here, we report a new and simple method for the scalable fabrication of all-inkjet-printed conductive microneedles based on silver nanoparticles (extensible to any other metallic nanoparticle ink) and a simple example of their application for monitoring the electrochemical properties of plants.

摘要

微针主要用于无痛给药以及可穿戴系统的生物传感。它们在精准农业等农学领域也很有前景，但微针的制造并不简单，通常需要昂贵的设备和洁净室协议，因此不适合大规模生产。在此，我们报告了一种基于银纳米颗粒（可扩展到任何其他金属纳米颗粒墨水）的全喷墨打印导电微针的可扩展制造新方法，并给出了一个其用于监测植物电化学特性的简单应用示例。