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使用机器人镊子型符合辐射探测器进行辐射源检测以精确定位淋巴结转移灶。

Radiation source detection for the accurate location of lymph node metastases using robotic forceps-type coincidence radiation detector.

作者信息

Kawamura Kazuya, Nakajima Ayano, Ito Shigeki, Takahashi Miwako, Yamaya Taiga

机构信息

Center for Frontier Medical Engineering, Chiba University, Chiba, Japan.

Graduate School of Science and Engineering, Chiba University, Chiba, Japan.

出版信息

Int J Comput Assist Radiol Surg. 2025 Apr;20(4):677-686. doi: 10.1007/s11548-024-03296-8. Epub 2024 Dec 2.

Abstract

PURPOSE

We have developed a forceps-type coincidence radiation detector for supporting lymph node dissection in esophageal cancer treatment. For precise detecting, this study aims to measure the 2D point-spread function of the detector at three difference tip angles, to devise a method to determine the position of a point source using the 2D point-spread function.

METHOD

The 2D sensitivity distribution on the surface of the detector was investigated to assess sensitivity variation caused by differences in the relative positions of the detector and radiation source. Based on the results, we identified the peak sensitivity value and proposed a detection method using this value. We evaluated the effectiveness of the proposed method by detecting radiation source location using this simulated distribution.

RESULT

From the radiation sensitivity distribution measurements, we observed a gradual decrease in radiation detection sensitivity from the center toward the edges of the detector surface. Additionally, we verified that the peak sensitivity value was attainable. Through the basic verification of the detection method, we confirmed that the radiation source location could be detected within a maximum error of 1.4 mm.

CONCLUSION

We developed a peak value search method aimed at mitigating sensitivity variations by leveraging the sensitivity distribution across the detector surface. The proposed device is thought to be able to quantitatively evaluate the desired target assuming that the field of view could be limited to the area clamped by the detector. As a next research step, more precise search methods should be verified in an environment resembling the one of the target clinical uses.

摘要

目的

我们开发了一种镊子型符合辐射探测器,用于支持食管癌治疗中的淋巴结清扫。为了精确检测,本研究旨在测量探测器在三个不同尖端角度下的二维点扩展函数,以设计一种使用二维点扩展函数确定点源位置的方法。

方法

研究了探测器表面的二维灵敏度分布,以评估探测器与辐射源相对位置差异引起的灵敏度变化。基于这些结果,我们确定了峰值灵敏度值,并提出了一种使用该值的检测方法。我们通过使用这种模拟分布检测辐射源位置来评估所提出方法的有效性。

结果

从辐射灵敏度分布测量中,我们观察到探测器表面从中心到边缘的辐射检测灵敏度逐渐降低。此外,我们验证了峰值灵敏度值是可以达到的。通过对检测方法的基本验证,我们确认可以在最大误差1.4毫米内检测到辐射源位置。

结论

我们开发了一种峰值搜索方法,旨在通过利用探测器表面的灵敏度分布来减轻灵敏度变化。假设视野可以限制在探测器夹住的区域内,所提出的设备被认为能够定量评估所需目标。作为下一步研究,应在类似于目标临床应用的环境中验证更精确的搜索方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d32b/12034586/98bbca77db8e/11548_2024_3296_Fig1_HTML.jpg

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