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静脉血栓栓塞病史患者在接受减重手术时使用下腔静脉滤器:一项美国外科医师学会肥胖症手术质量改进计划(MBSAQIP)研究

IVC filter use in patients with a history of venous thromboembolism undergoing bariatric surgery: a MBSAQIP study.

作者信息

Gontarz Brendan, Seip Richard, Staff Ilene, Santana Connie, McLaughlin Tara, Bond Dale, Tishler Darren, Papasavas Pavlos

机构信息

Department of Surgery, Hartford Hospital, Hartford, CT, 06102, USA.

Hartford Hospital Metabolic and Bariatric Surgery Program, 80 Seymour Street, Hartford, CT, 06106, USA.

出版信息

Surg Endosc. 2025 Feb;39(2):875-880. doi: 10.1007/s00464-024-11395-5. Epub 2024 Dec 2.

Abstract

BACKGROUND

Research on the use of prophylactic inferior vena cave filter (IVCF) placement prior to metabolic and bariatric surgery (MBS) in high risk patients has yielded conflicting results. We evaluated thrombotic events and mortality in patients with a history of venous thromboembolism (VTE) who underwent IVCF placement in anticipation of MBS.

METHODS

We queried the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database for all patients undergoing primary sleeve gastrectomy or Roux-en-Y gastric bypass from 2015 to 2019 with a history of VTE. We tabulated yearly IVCF use and compared 30-day rates of deep venous thrombosis (DVT), pulmonary embolism (PE), readmission, mortality, and serious adverse events in patients with and without prophylactic IVCF placement. Multivariate logistic regression was used to assess the relationship between preoperative placement of an IVCF and postoperative outcomes.

RESULTS

Of 754,397 patients undergoing MBS, 16,683 (2.2%) had a prior VTE. Placement of IVCF in anticipation of MBS decreased from 285/2245 (10.4%) in 2015 to 85/3750 (2.2%) in 2019 (p < 0.01). The incidence of PE did not differ significantly between patients with prophylactic IVCF vs. those without (0.1% vs 0.5%, p = 0.13). Postoperative DVT was more common in patients who underwent IVCF placement (1.7% vs. 0.8%, p < 0.01). No significant differences were observed in mortality. Preoperative placement of an IVCF was an independent risk factor for development of a postoperative DVT (OR 2.45; 95% CI 1.39-4.32).

CONCLUSIONS

These data do not support a history of VTE as an indication for prophylactic IVCF placement in anticipation of MBS.

摘要

背景

对于在代谢和减重手术(MBS)前对高危患者预防性放置下腔静脉滤器(IVCF)的研究结果存在矛盾。我们评估了有静脉血栓栓塞(VTE)病史且因预期进行MBS而接受IVCF放置的患者的血栓形成事件和死亡率。

方法

我们查询了代谢和减重手术认证与质量改进计划(MBSAQIP)数据库,以获取2015年至2019年期间所有接受初次袖状胃切除术或Roux-en-Y胃旁路手术且有VTE病史的患者。我们列出了每年IVCF的使用情况,并比较了预防性放置IVCF和未放置IVCF的患者的30天深静脉血栓形成(DVT)、肺栓塞(PE)、再入院、死亡率和严重不良事件发生率。采用多因素逻辑回归分析评估术前放置IVCF与术后结局之间的关系。

结果

在754397例接受MBS的患者中,16683例(2.2%)有既往VTE病史。因预期进行MBS而放置IVCF的比例从2015年的285/2245(10.4%)降至2019年的85/3750(2.2%)(p<0.01)。预防性放置IVCF的患者与未放置的患者之间PE的发生率无显著差异(0.1%对0.5%,p=0.13)。接受IVCF放置的患者术后DVT更常见(1.7%对0.8%,p<0.01)。死亡率无显著差异。术前放置IVCF是术后发生DVT的独立危险因素(OR 2.45;95%CI 1.39-4.32)。

结论

这些数据不支持将VTE病史作为预期进行MBS时预防性放置IVCF的指征。

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