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复发性食管旁疝修补术中患者报告的结局和决策后悔评分

Patient reported outcomes and decision regret scores in redo-paraesophageal hernia repair.

作者信息

Remulla Daphne, Maskal Sara M, Ellis Ryan C, Woo Kimberly P, Bennet William C, Fafaj Aldo, Navarrete Salvador, Krpata David M, Miller Benjamin T, Petro Clayton C, Prabhu Ajita S, Rosen Michael J, Beffa Lucas R

机构信息

Department of General Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.

Department of Surgery, University of Tennessee Medical Center-Knoxville, Knoxville, TN, USA.

出版信息

Surg Endosc. 2025 Feb;39(2):850-858. doi: 10.1007/s00464-024-11415-4. Epub 2024 Dec 2.

Abstract

INTRODUCTION

Recurrent paraesophageal hernia (PEH) repair presents significant technical challenges, with limited data weighing the benefit to the operative risk. This study aims to describe our experience with recurrent PEH repair, including long-term surgical and patient reported outcomes (PROs).

METHODS

We conducted a retrospective review of recurrent PEH repairs from June 2018-March 2023 using our institutional database. A blinded review of post-operative imaging was conducted to assess for recurrence. Quality of life (QOL) and decision regret were measured using the GERD Health-Related Quality-of-Life (GERD-HRQL) questionnaire and Decision Regret Scale (DRS) at maximum follow up.

RESULTS

Eighty-eight patients underwent recurrent PEH repair at our institution for PEH, classified as type II (13.6%), type III (72.7%) and type IV (13.6%). There was significant heterogeneity in operative techniques used: one-third of patients had mesh placed at the hiatus, 11.4% had a Collis gastroplasty, and one-third of patients underwent fundoplication. Intraoperative complications included gastric (5.7%), esophageal (2.3%), vascular (1.1%) and pulmonary (1.1%) injuries. Follow up was available for 73 patients with median follow up of 35.2 months. Of patients with radiographic follow up, 20 (35.7%) had a radiographic recurrence: 12 (21.4%) were 2-5 cm and 8 (14.3%) were > 5 cm. Patients reporting PROs (53 patients; 60.2%) reported low symptom severity (mean GERD-HRQL 13.1 ± 12) and low decision regret (mean DRS 13.3 ± 19.4) with 75.5% scoring in the lowest quartile (DRS < 25). Radiographic recurrence was associated with worse QOL (p < 0.05), but no significant difference in decision regret (p = 0.125).

CONCLUSION

We found significant heterogeneity amongst recurrent PEH repair techniques with continued high recurrence rate during follow up. Radiographic recurrence was correlated with worse QOL, yet patients reported low symptom severity and low decision regret, suggesting continued value in these challenging operations. Future studies should aim to identify more effective techniques to reduce recurrence rates in this patient population.

摘要

引言

复发性食管旁疝(PEH)修复术面临重大技术挑战,权衡手术风险与获益的数据有限。本研究旨在描述我们复发性PEH修复术的经验,包括长期手术结果及患者报告结局(PROs)。

方法

我们使用机构数据库对2018年6月至2023年3月期间的复发性PEH修复术进行了回顾性研究。对术后影像学检查进行盲法评估以判断是否复发。在最长随访期使用GERD健康相关生活质量(GERD-HRQL)问卷和决策后悔量表(DRS)测量生活质量(QOL)和决策后悔程度。

结果

88例患者在我们机构接受了复发性PEH修复术治疗PEH,分类为II型(13.6%)、III型(72.7%)和IV型(13.6%)。所采用的手术技术存在显著异质性:三分之一的患者在裂孔处放置了补片;11.4%的患者进行了科利斯胃成形术;三分之一的患者接受了胃底折叠术。术中并发症包括胃部损伤(5.7%)、食管损伤(2.3%)、血管损伤(1.1%)和肺部损伤(1.1%)。73例患者获得随访,中位随访时间为35.2个月。在接受影像学随访的患者中,20例(35.7%)出现影像学复发:12例(21.4%)复发范围为2 - 5厘米,8例(共14.3%)复发范围>5厘米。报告PROs的患者(53例;60.2%)症状严重程度较低(GERD-HRQL平均为13.1±12),决策后悔程度较低(DRS平均为13.3±19.4),75.5%的患者在最低四分位数(DRS<25)范围内。影像学复发与较差的QOL相关(p<0.05),但在决策后悔程度方面无显著差异(p = 0.125)。

结论

我们发现复发性PEH修复技术存在显著异质性,随访期间复发率持续较高。影像学复发与较差的QOL相关,但患者报告的症状严重程度较低且决策后悔程度较低,这表明这些具有挑战性的手术仍有价值。未来的研究应致力于确定更有效的技术以降低该患者群体的复发率。

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