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在食管旁疝修补术时进行胃底折叠术并不能降低疝复发率或术后反流率。

Fundoplication at the time of paraesophageal hernia repair does not decrease the rate of hernia recurrence or postoperative reflux.

作者信息

Lyons Joshua, Chatha Hamza Nasir, Boutros Christina, Khan Saher-Zahra, Benson Jamie, Katz Guy, Levine Iris, Alvarado Christine, Wieland Patrick, Marks Jeffrey

机构信息

Department of Surgery, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Lakeside 7, Cleveland, OH, 44106, USA.

Department of Surgery, Case Western Reserve University, Cleveland, OH, USA.

出版信息

Surg Endosc. 2025 Jan;39(1):577-581. doi: 10.1007/s00464-024-11317-5. Epub 2024 Oct 24.

Abstract

BACKGROUND

Fundoplication at the time of paraesophageal hernia (PEH) repair is thought to help prevent the development or persistence of postoperative gastroesophageal reflux (GERD) and might also prevent hernia recurrence. However, the published data is not strong enough to definitively recommend this approach. This study was designed to evaluate the effectiveness and complications of a fundoplication at the time of paraesophageal hernia repair.

METHODS

This was a retrospective cohort study of all patients who underwent a paraesophageal hernia repair at a single institution over a 14 year period from 2010 to 2023. Patients were divided into 2 cohorts, those who underwent fundoplication at the time of PEH repair and those who did not. Rates of PEH recurrence, rates of reoperation for a recurrent PEH, postoperative dysphagia rates, and postoperative GERD rates were then compared between the two cohorts.

RESULTS

There were 1,155 patients included in the study. There were 610 (53%) patients who underwent PEH repair with fundoplication and 545 (47%) who did not undergo a fundoplication. 113 (19%) of the patients who underwent fundoplication developed a hernia recurrence compared to 67 (12%) who had a PEH repair alone (p = 0.004). However, each cohort had similar rates of requiring reoperation (p = 0.4). Inclusion of a fundoplication did lead to higher rates of postoperative dysphagia > 30 days postoperatively, 12% vs 7% (p = 0.002), but did not lead to decreased rates of symptomatic GERD postoperatively, 7% with a fundoplication and 7% without (p = 0.93).

CONCLUSION

In this present study, fundoplication at the time of PEH repair did not prevent hernia recurrence, need for reoperation, or decrease postoperative GERD rates but does increase postoperative dysphagia. While there are definite indications for fundoplication at the time of PEH repair (i.e., type 1 hernia), these data do not support the routine use of fundoplication during PEH repair with a normal gastroesophageal flap valve intraoperatively.

摘要

背景

食管旁疝(PEH)修补术同期行胃底折叠术被认为有助于预防术后胃食管反流(GERD)的发生或持续存在,也可能预防疝复发。然而,已发表的数据不足以明确推荐这种方法。本研究旨在评估食管旁疝修补术同期行胃底折叠术的有效性和并发症。

方法

这是一项对2010年至2023年期间在单一机构接受食管旁疝修补术的所有患者进行的回顾性队列研究。患者分为两组,一组在PEH修补术同期行胃底折叠术,另一组未行该手术。然后比较两组之间PEH复发率、复发性PEH再次手术率、术后吞咽困难率和术后GERD率。

结果

本研究共纳入1155例患者。其中610例(53%)患者在PEH修补术同期行胃底折叠术,545例(47%)患者未行胃底折叠术。行胃底折叠术的患者中有113例(19%)发生疝复发,而单纯行PEH修补术的患者中有67例(12%)复发(p = 0.004)。然而,两组的再次手术率相似(p = 0.4)。行胃底折叠术确实导致术后30天以上吞咽困难发生率更高,分别为12%和7%(p = 0.002),但并未导致术后有症状GERD发生率降低,行胃底折叠术组和未行该手术组均为7%(p = 0.93)。

结论

在本研究中,PEH修补术同期行胃底折叠术并不能预防疝复发、再次手术的需要,也不能降低术后GERD发生率,但会增加术后吞咽困难。虽然PEH修补术同期行胃底折叠术有明确的指征(即1型疝),但这些数据不支持在术中胃食管瓣正常的PEH修补术中常规使用胃底折叠术。

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