Saragoça Andreia, Canha Henrique, Varanda Carla M R, Materatski Patrick, Cordeiro Ana Isabel, Gama José
Biosciences School of Elvas, Polytechnic Institute of Portalegre, Elvas, Portugal.
MED-Mediterranean Institute for Agriculture, Environment and Development, & CHANGE-Global Change and Sustainability Institute, Institute for Advanced Studies and Research, Pólo da Mitra, Ap. 94, Évora, 7006-554, Portugal.
Environ Microbiol Rep. 2024 Dec;16(6):e70021. doi: 10.1111/1758-2229.70021.
Biological control agents (BCAs) are beneficial living organisms used in plant protection to control pathogens sustainably. Lactic acid bacteria (LAB) have gained attention in biopesticides due to their safety as recognized by the Food and Drug Administration. These bacteria possess antifungal properties, demonstrating inhibitory effects through nutrient competition or the production of antimicrobial metabolites. Numerous Lactobacillus species have shown the ability to inhibit pathogenic microorganisms, primarily through acid production. The organic acids secreted by LAB reduce the pH of the medium, creating a hostile environment for microorganisms. These organic acids are a primary inhibition mechanism of LAB. This article reviews several studies on LAB as BCAs, focusing on their inhibition modes. Additionally, it discusses the limitations and future challenges of using LAB to control phytopathogens for sustainable agriculture.
生物防治剂（BCAs）是用于植物保护以可持续控制病原体的有益生物。乳酸菌（LAB）因其被食品药品监督管理局认可的安全性而在生物农药领域受到关注。这些细菌具有抗真菌特性，通过营养竞争或产生抗菌代谢物发挥抑制作用。许多乳酸杆菌属物种已显示出抑制致病微生物的能力，主要是通过产酸。乳酸菌分泌的有机酸会降低培养基的pH值，为微生物创造不利环境。这些有机酸是乳酸菌的主要抑制机制。本文综述了几项关于乳酸菌作为生物防治剂的研究，重点关注其抑制模式。此外，还讨论了使用乳酸菌控制植物病原体以实现可持续农业的局限性和未来挑战。
