Chen Minfeng, Zhao Sijun, Peng Lulu, Rong Yu, Zhu Chengwei, Lu Fan, Mao Xinjie
Optometry Clinic Center, Wenzhou Medical University Eye Hospital, Wenzhou, Zhejiang, China.
Front Neurosci. 2024 Nov 18;18:1424394. doi: 10.3389/fnins.2024.1424394. eCollection 2024.
The study analyzed the changes in corneal surface shape after replacing orthokeratology lenses carrying a small base curve (BC) diameter.
In this retrospective study, we included ~54 right eyes belonging to 54 myopic children who insisted on wearing an orthokeratology (ortho-k BC 6.0 mm) lens for more than 12 months and then replaced the second ortho-k (BC 6.0 mm or BC 5.0 mm) lens ~12 months. The children were categorized into two groups based on the design of the BC of the replaced ortho-k lens 6.0/5.0 and 6.0/6.0.
The ratio of axial length (AL) elongation in the 6.0/5.0 group was significantly less than in the 6.0/6.0 group (-0.015 ± 0.014 mm/M vs. -0.005 ± 0.012 mm/M, = -2.672, = 0.010). After replacing the BC 5.0 ortho-k lens, the optical zone (8.19 ± 2.60 mm vs. 9.64 ± 1.57 mm, = -2.345, = 0.023), reverse zone (31.64 ± 5.80 mm vs. 34.86 ± 4.61 mm, = -2.169, = 0.035), and treatment zone (17.16 ± 3.94 mm vs. 22.96 ± 2.59 mm, = -6.049, < 0.001) were all smaller than those in the 6.0/6.0 group. In the 6.0/5.0 group, the optical zone (wearing more than 1 month as first: 11.16 ± 2.12 mm, the last inspection before replacing lens as before: 10.87 ± 1.90 mm), reverse curve zone (first: 22.03 ± 3.11 mm, before: 26.24 ± 5.06 mm), and treatment zone (first: 35.97 ± 5.54 mm, before: 37.11 ± 6.04 mm) were all greater than these after replacing ortho-k lens (all < 0.001).
Replacing an ortho-k lens with a smaller BC resulted in a larger decrease in the mean central corneal zone and a substantial increase in the paracentral corneal zone. In addition, the ortho-k lens with a smaller BC does not increase the decentration distance and contributes to effective myopia control.
本研究分析了更换小基弧（BC）直径的角膜塑形镜后角膜表面形状的变化。
在这项回顾性研究中，我们纳入了54名近视儿童的约54只右眼，这些儿童坚持佩戴角膜塑形镜（角膜塑形术BC 6.0 mm）超过12个月，然后在约12个月后更换了第二副角膜塑形镜（BC 6.0 mm或BC 5.0 mm）。根据更换的角膜塑形镜BC的设计，将儿童分为两组，即6.0/5.0组和6.0/6.0组。
6.0/5.0组的眼轴长度（AL）伸长率显著低于6.0/6.0组（-0.015±0.014 mm/M对-0.005±0.012 mm/M，t = -2.672，P = 0.010）。更换BC 5.0的角膜塑形镜后，光学区（8.19±2.60 mm对9.64±1.57 mm，t = -2.345，P = 0.023）、反转区（31.64±5.80 mm对34.86±4.61 mm，t = -2.169，P = 0.035）和治疗区（17.16±3.94 mm对22.96±2.59 mm，t = -6.049，P < 0.001）均小于6.0/6.0组。在6.0/5.0组中，光学区（首次佩戴超过1个月时：11.16±2.12 mm，更换镜片前最后一次检查时：10.87±1.90 mm）、反转曲线区（首次：22.03±3.11 mm，之前：26.24±5.06 mm）和治疗区（首次：35.97±5.54 mm，之前：37.11±6.04 mm）均大于更换角膜塑形镜后（均P < 0.001）。
更换较小BC的角膜塑形镜会导致中央角膜平均区域更大程度的减小和旁中央角膜区域的显著增加。此外，较小BC的角膜塑形镜不会增加偏心距离，有助于有效控制近视。
