角膜塑形术治疗区偏心对近视进展的影响。
The effect of orthokeratology treatment zone decentration on myopia progression.
机构信息
Beijing Tongren Eye Center, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology and visual Sciences, National Engineering Research Center for Ophthalmology, #1 Dong Jiao Min Xiang, Beijing, 100730, China.
Key Laboratory of Universal Wireless Communications, Ministry of Education, Beijing University of Posts and Telecommunications, Beijing, 100876, China.
出版信息
BMC Ophthalmol. 2022 Feb 15;22(1):76. doi: 10.1186/s12886-022-02310-4.
BACKGROUND
This study aimed to compare the changes in the axial length (AL) in myopic children that wear centered and decentered orthokeratology (Ortho-K).
METHODS
This retrospective study included 217 subjects who were treated with an Ortho-K lens for >12 months. The subjects were divided into three groups based on the magnitude of the Ortho-K lens treatment zone decentration: mildly, moderately, and severely decentered groups. Distance and direction of treatment zone decentration were calculated using software that was developed in-house. The AL changes in different groups were compared.
RESULTS
Based on the distance of the treatment zone decentration, 65 children (65 eyes) were included in the mildly decentered group, 114 children (114 eyes) in the moderately decentered group, and 38 children (38 eyes) in the severely decentered group. The mean decentration distance in the three groups was 0.35 ± 0.11 mm, 0.71 ± 0.13 mm, and 1.21 ± 0.22 mm, respectively. The mean AL increase in the three groups after 12 months of Ortho-K lens wear was 0.24 ± 0.21 mm, 0.23 ± 0.18 mm, and 0.19 ± 0.20 mm, respectively. There were no significant differences in AL changes among the three groups.
CONCLUSIONS
Ortho-K lens decentration is common in clinical practice. The AL change after Ortho-K lens wear was not significantly different in subjects with different magnitudes of Ortho-K lens decentration. Fitting the Ortho-K lens in the properly centered zone is recommended to ensure the safety of Ortho-K lens wear and to maintain visual quality.
背景
本研究旨在比较中心定位和偏心定位角膜塑形术（Ortho-K）对近视儿童眼轴长度（AL）变化的影响。
方法
本回顾性研究纳入了 217 名接受 Ortho-K 镜片治疗>12 个月的患者。根据 Ortho-K 镜片治疗区偏心量的大小，将患者分为三组：轻度偏心组、中度偏心组和重度偏心组。使用自主开发的软件计算治疗区偏心的距离和方向。比较各组之间的 AL 变化。
结果
根据治疗区偏心距离，轻度偏心组纳入 65 例（65 眼），中度偏心组纳入 114 例（114 眼），重度偏心组纳入 38 例（38 眼）。三组的平均偏心距离分别为 0.35±0.11mm、0.71±0.13mm 和 1.21±0.22mm。三组佩戴 Ortho-K 镜片 12 个月后，AL 平均增加量分别为 0.24±0.21mm、0.23±0.18mm 和 0.19±0.20mm。三组间 AL 变化差异无统计学意义。
结论
临床实践中 Ortho-K 镜片偏心较为常见。在偏心量不同的患者中，佩戴 Ortho-K 镜片后 AL 的变化无显著差异。建议将 Ortho-K 镜片适配在适当的中心区域，以确保 Ortho-K 镜片佩戴的安全性和视觉质量。
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