Zhou Jianshun, Guo Mingling, Wang Jiasheng, Hu Qian, Liu Yingying, Chen Zhen, Lu Feng, Lin Yong, Zhong Maolin, Wang Lifeng
The First Clinical Medical College of Gannan Medical University, Ganzhou, Jiangxi, People's Republic of China.
Department of Anesthesiology, Ganzhou Cancer Hospital, Ganzhou, Jiangxi, People's Republic of China.
Orthop Res Rev. 2024 Nov 27;16:283-293. doi: 10.2147/ORR.S489775. eCollection 2024.
The aim of this study was to observe the intraoperative and postoperative analgesic effects of suprainguinal fascia iliaca compartment block (SFICB) combined with sciatic nerve block (SNB) in patients undergoing total hip arthroplasty (THA).
Eighty-seven THA patients were randomly assigned to three groups: general anesthesia (Group C), general anesthesia with SFICB (Group F), and general anesthesia with SFICB and SNB (Group F+S). Numeric Rating Scale (NRS) scores were used to evaluate pain levels at rest and during activity at various postoperative time points. The secondary outcomes included heart rate (HR), mean arterial pressure (MAP), intraoperative sufentanil consumption, number of effective presses on the analgesic pump, rescue analgesic administration, postoperative nausea and vomiting, and serum levels of IL-1β and TNF-α.
NRS scores were significantly lower in Groups F and F+S compared to Group C at different postoperative time points both at rest and during activity (P<0.05). Intraoperative sufentanil consumption, the number of effective presses on the analgesic pump, rescue analgesic administration, and postoperative nausea and vomiting were lower in Groups F and F+S compared to Group C (P<0.05). There were also significant differences in sufentanil consumption and the number of effective presses on the analgesic pump between groups F and F+S (P<0.05). The expression levels of IL-1β and TNF-α were lower in groups F and F+S compared to group C (P<0.05) at specific time points.
The application of ultrasound-guided SFICB combined with SNB for total hip arthroplasty can provide more comprehensive analgesia, reduce postoperative NRS scores, alleviate haemodynamic fluctuations, decrease opioid drug use, and reduce the serum levels of inflammatory factors, especially when combined with SNB.
本研究旨在观察腹股沟上髂筋膜间隙阻滞(SFICB)联合坐骨神经阻滞(SNB)在全髋关节置换术(THA)患者中的术中和术后镇痛效果。
87例THA患者随机分为三组:全身麻醉组(C组)、全身麻醉联合SFICB组(F组)和全身麻醉联合SFICB及SNB组(F+S组)。采用数字评分量表(NRS)评估术后不同时间点静息和活动时的疼痛程度。次要观察指标包括心率(HR)、平均动脉压(MAP)、术中舒芬太尼用量、镇痛泵有效按压次数、补救性镇痛药物使用情况、术后恶心呕吐以及血清白细胞介素-1β(IL-1β)和肿瘤坏死因子-α(TNF-α)水平。
F组和F+S组在术后不同时间点静息和活动时的NRS评分均显著低于C组(P<0.05)。F组和F+S组的术中舒芬太尼用量、镇痛泵有效按压次数、补救性镇痛药物使用情况及术后恶心呕吐发生率均低于C组(P<0.05)。F组和F+S组在舒芬太尼用量和镇痛泵有效按压次数方面也存在显著差异(P<0.05)。在特定时间点,F组和F+S组的IL-1β和TNF-α表达水平低于C组(P<0.05)。
超声引导下SFICB联合SNB应用于全髋关节置换术可提供更全面的镇痛效果,降低术后NRS评分,减轻血流动力学波动,减少阿片类药物使用,并降低炎症因子血清水平,尤其是联合SNB时。