Maddali Radhika, Alvarez-Gell Carmen, Balasundaram Palanikumar, Sakr Mohamed
Department of Neonatal-Perinatal Medicine, Montefiore Medical Center, Bronx, USA.
Department of Pediatrics, Flushing Hospital Medical Center, Flushing, USA.
Cureus. 2024 Nov 1;16(11):e72860. doi: 10.7759/cureus.72860. eCollection 2024 Nov.
Meconium peritonitis (MP) as a cause of non-immune hydrops in neonates is rarely reported. We present a case of a 35-week gestational-age male neonate diagnosed with hydrops secondary to MP. Antenatal scan at 34 weeks and five days revealed features of fetal hydrops, and the prenatal workup did not reveal the etiology. Postnatal imaging confirmed MP with abdominal calcifications, and the neonate developed pneumoperitoneum due to intestinal perforation. Emergency laparotomy revealed diffuse MP without a definitive site of perforation. An ileostomy was created and closed before discharge. Follow-up showed normal growth and development, emphasizing the importance of early diagnosis and multidisciplinary management in such rare cases. MP, though rare, should be considered in the differential diagnosis of non-immune hydrops fetalis (NIHF), particularly in the presence of fetal ascites.
胎粪性腹膜炎（MP）作为新生儿非免疫性水肿的病因鲜有报道。我们报告一例孕35周的男性新生儿，诊断为继发于MP的水肿。孕34周零5天的产前超声检查发现胎儿水肿特征，产前检查未明确病因。产后影像学检查确诊为MP伴腹部钙化，新生儿因肠穿孔出现气腹。急诊剖腹探查显示弥漫性MP，无明确穿孔部位。行回肠造口术，并在出院前关闭。随访显示生长发育正常，强调了在这类罕见病例中早期诊断和多学科管理的重要性。MP虽然罕见，但在胎儿非免疫性水肿（NIHF）的鉴别诊断中应予以考虑，尤其是在存在胎儿腹水的情况下。
