不同病因导致的同胞兄妹患胎粪性腹膜炎：病例报告。
Meconium peritonitis resulting from different etiologies in siblings: a case report.
机构信息
Department of Pediatrics, Pusan National University Hospital, Pusan National University School of Medicine, Busan, South Korea.
Department of Pediatrics, Pusan National University Children's Hospital, Pusan National University School of Medicine, 20 Geumo-ro, Yangsan, 50612, South Korea.
出版信息
BMC Pediatr. 2020 Mar 5;20(1):106. doi: 10.1186/s12887-020-2016-3.
BACKGROUND
Meconium peritonitis is defined as aseptic chemical inflammation caused by intrauterine bowel perforation. The underlying causes of bowel perforation include intestinal atresia, midgut volvulus, intussusception, congenital bands, and meconium ileus.
CASE PRESENTATION
Siblings with prenatally diagnosed meconium peritonitis of different etiologies were found. The elder sister was born at 36 + 6 weeks gestation with a birth weight of 3110 g. She was diagnosed with meconium peritonitis caused by ileal atresia. Two years later, the younger brother was born at 34 + 3 weeks gestation with a birth weight of 2850 g. He was diagnosed with meconium peritonitis caused by midgut volvulus.
CONCLUSIONS
Among the previously reported cases of meconium peritonitis, familial occurance of meconium peritonitis is extremely rare. We present a case of prenatally diagnosed meconium peritonitis in siblings to promote further understanding of its etiology and clinical course.
背景
胎粪性腹膜炎是指由于胎儿肠穿孔导致的无菌性化学性炎症。肠穿孔的潜在原因包括肠闭锁、中肠扭转、肠套叠、先天性索带和胎粪性肠梗阻。
病例介绍
发现有不同病因的胎粪性腹膜炎的同胞兄妹。姐姐于 36+6 周妊娠时出生，出生体重为 3110g。她被诊断为回肠闭锁引起的胎粪性腹膜炎。两年后，弟弟于 34+3 周妊娠时出生，出生体重为 2850g。他被诊断为中肠扭转引起的胎粪性腹膜炎。
结论
在之前报道的胎粪性腹膜炎病例中，胎粪性腹膜炎的家族性发生极为罕见。我们报告了一例同胞兄妹的产前诊断胎粪性腹膜炎病例，以促进对其病因和临床病程的进一步了解。
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